DUSP4 Antibody

Images

 
Western Blot: DUSP4 Antibody [NBP1-19592] - Analysis of DUSP4 Antibody at 1:500 dilutionLane1:A549 whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:PC12 whole cell lysate
Immunohistochemistry-Paraffin: DUSP4 Antibody [NBP1-19592] - Paraffin-embedded human breast carcinoma tissue at 1:50.
Western Blot: DUSP4 Antibody [NBP1-19592] - extracts from RAW264.7
Immunohistochemistry-Paraffin: DUSP4 Antibody [NBP1-19592] - Paraffin-embedded human brain tissue.

Product Details

Summary
Product Discontinued
View other related DUSP4 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-19592
    • Availability
      Product Discontinued

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DUSP4 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 80-130 of Human MKP-2.
Clonality
Polyclonal
Host
Rabbit
Gene
DUSP4
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunohistochemistry 1:50-1:200
  • Immunohistochemistry-Paraffin 1:50-1:200
Application Notes
Western blot (WB) analysis of MKP-2 (Y108) pAb in extracts from RAW264.7Immunohistochemistry (IHC) analyzes of MKP-2 (Y108) pAb in paraffin-embedded human brain tissue.
Theoretical MW
44 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publication using NBP1-19592.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for DUSP4 Antibody

  • dual specificity phosphatase 4
  • Dual specificity protein phosphatase hVH2
  • EC 3.1.3.16
  • EC 3.1.3.48
  • HVH2serine/threonine specific protein phosphatase
  • MAP kinase phosphatase 2
  • Mitogen-activated protein kinase phosphatase 2
  • MKP-2dual specificity protein phosphatase 4
  • MKP2VH1 homologous phosphatase 2
  • TYP
  • VH2

Background

Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), VHR, PAC1, MKP-2, hVH-3 (B23), hVH-5, MKP-3, MKP-X, and MKP- 4. Human MKP-2 maps to chromosome 8p12-p11 and encodes a 394 amino acid, 43 kDa protein that specifically inactivates ERK1, ERK2 and JNK.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for DUSP4 Antibody (NBP1-19592)(1)

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol DUSP4
Entrez
Uniprot