DRAK2 Antibody - Pre-diluted

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
Pre-diluted

Order Details

DRAK2 Antibody - Pre-diluted Summary

Immunogen
Synthetic peptide corresponding to C-terminal of of human DRAK2 protein.
Specificity
This product is specific for DRAK2
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
STK17B
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin Neat
Application Notes
IHC-P: Ready diluted. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user.

Reactivity Notes

This product is specific for Human.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Prediluted antibody
Preservative
No Preservative
Purity
Immunogen affinity purified

Alternate Names for DRAK2 Antibody - Pre-diluted

  • DAP kinase-related apoptosis-inducing protein kinase 2
  • DRAK2
  • DRAK2death-associated protein kinase-related 2
  • EC 2.7.11
  • EC 2.7.11.1
  • serine/threonine kinase 17b (apoptosis-inducing)
  • serine/threonine kinase 17b
  • serine/threonine-protein kinase 17B
  • STK17B

Background

Protein kinases play important roles in the signal transduction in response to a variety of external stimuli. Recently, several protein kinases have been identified that may also be involved in apoptotic process. Overexpression of a serine/threonine kinase, ZIP kinase can cause the morphological changes typical of apoptosis in NIH 3T3 cells (1). Sanjo et al, have identified two new protein kinases DRAK1 and DRAK2 (Death Receptor Associated Kinase 1 and 2) (1). Both DRAKs and ZIP kinase share significant homology at the amino acid level (1,2). The kinase domains of both DRAKs, ZIP kinase are homologous to DAP (Death-associated protein) kinase, which is involved in the apoptotic signaling induced by interferon-g. Overexpression of DRAKs in NIH 3T3 cells lead to apoptosis. These transfection experiments suggest that C-terminal domain of DRAKs are important for induction of apoptosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol STK17B
Entrez