DPYSL4 Antibody


Western Blot: DPYSL4 Antibody [NBP1-51355] - Extracts from hela cells.

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DPYSL4 Antibody Summary

Synthetic peptide, corresponding to amino acids 111-160 of Human CRMP-3.
CRMP-3 (C132) pAb detects endogenous levels of CRMP-3 protein.
Immunogen affinity purified
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  • Western Blot 1:500-1:1000
Application Notes
Western blot (WB) analysis of CRMP-3 (C132) pAb in extracts from HT-29 cells.
Theoretical MW
50 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human, Mouse, Rat

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.2)
15mM Sodium Azide
1.0 mg/ml
Immunogen affinity purified

Alternate Names for DPYSL4 Antibody

  • CRMP-3
  • CRMP3Collapsin response mediator protein 3
  • dihydropyrimidinase-like 4
  • dihydropyrimidinase-related protein 4
  • DRP-4UNC33-like phosphoprotein 4


Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to Semaphorin 3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. CRMP-3 is expressed transiently in developing spinal cord and selectively in the postnatal cerebellum. It is cleaved by Calpain to produce a p54 N-terminal fragment. This cleavage product translocates to the nucleus and induces neuronal death in response to excitotoxicity and cerebral ischemia.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Gene Symbol DPYSL4