DOK2 Antibody - Pre-diluted

Images

 
There are currently no images for DOK2 Antibody (NBP1-35777).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
Pre-diluted

Order Details

DOK2 Antibody - Pre-diluted Summary

Immunogen
Synthetic peptide corresponding to C-terminal of human DOK2 protein.
Specificity
This product is specific for DOK2
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DOK2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin Neat
Application Notes
IHC-P: Use at an assay dependent dilution. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user.

Reactivity Notes

This product is specific for Human.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Prediluted antibody
Preservative
No Preservative
Purity
Immunogen affinity purified

Alternate Names for DOK2 Antibody - Pre-diluted

  • docking protein 2
  • docking protein 2, 56kD
  • docking protein 2, 56kDa
  • Dok-2
  • Downstream of tyrosine kinase 2
  • p56(dok-2)
  • p56DOK
  • p56dok-2

Background

Docking proteins interact with receptor tyrosine kinases and mediate particular biological responses using signal transduction. DOK2 acts as a multiple docking protein downstream of receptor or non-receptor tyrosine kinases. By this mechanism it acts to negatively regulate signal transduction and cell proliferation controlled by cytokines in a feedback loop. DOK2 is highly expressed in cells and tissues of hematopoietic origin as well as in lung. Expression of bcr/abl induces additional tyrosine phosphorylation of the DOK1 and DOK2 proteins and their association with Ras-GAP. Thus, it is suspected that DOK association regulates GAP activity toward Ras and that the DOK proteins serve as mediators of bcr-abl signaling. The role of DOK proteins in bcr-abl regulation may also be implicated in chronic myelogenous leukemia (CML), which is characterized by a Philadelphia chromosome translocation t(9;22). Such a mutation would result in a p210-bcr/abl chimeric protein-tyrosine kinase which has been found in many CML cases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NB100-82112
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
H00000420-B01P
Species: Hu
Applications: WB
AF5094
Species: Hu, Mu, Rt
Applications: WB
AF2554
Species: Mu
Applications: WB, Flow, CyTOF-ready, ICC
AF2685
Species: Hu
Applications: WB, Simple Western, IHC
NBP1-84084
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
MAB2317
Species: Hu, Mu, Rt
Applications: WB, ICC
NBP1-80959
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-46218
Species: Hu
Applications: WB, IHC
MAB7008
Species: Hu
Applications: WB, ICC
NBP2-02340
Species: Hu, Mu, Rt, Mk
Applications: WB, Flow, ICC/IF, IHC, IHC-P
AF2724
Species: Hu, Mu, Rt
Applications: WB, Simple Western, Flow, IHC, CyTOF-ready
AF5414
Species: Hu
Applications: WB, Simple Western
NB100-524
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP, Flow-IC
H00003117-M01
Species: Hu
Applications: WB, ELISA, PLA
NBP1-35777
Species: Hu
Applications: IHC, IHC-P

Publications for DOK2 Antibody (NBP1-35777) (0)

There are no publications for DOK2 Antibody (NBP1-35777).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for DOK2 Antibody (NBP1-35777) (0)

There are no reviews for DOK2 Antibody (NBP1-35777). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for DOK2 Antibody (NBP1-35777) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional DOK2 Products

Bioinformatics Tool for DOK2 Antibody (NBP1-35777)

Discover related pathways, diseases and genes to DOK2 Antibody (NBP1-35777). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for DOK2 Antibody (NBP1-35777)

Discover more about diseases related to DOK2 Antibody (NBP1-35777).
 

Pathways for DOK2 Antibody (NBP1-35777)

View related products by pathway.

PTMs for DOK2 Antibody (NBP1-35777)

Learn more about PTMs related to DOK2 Antibody (NBP1-35777).
 

Research Areas for DOK2 Antibody (NBP1-35777)

Find related products by research area.

Blogs on DOK2

There are no specific blogs for DOK2, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our DOK2 Antibody - Pre-diluted and receive a gift card or discount.

Bioinformatics

Gene Symbol DOK2
Entrez