DNAM-1/CD226 Antibody

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Western Blot: DNAM-1/CD226 Antibody [NBP1-00745] - Analysis of CD226 (Y325) antibody in extracts from 293 cells treated with PMA 125ng/ml 30'

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-00745
    • Availability
      Product Discontinued

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DNAM-1/CD226 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 293-342 of Human DNAM-1.
Clonality
Polyclonal
Host
Rabbit
Gene
CD226
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunocytochemistry/Immunofluorescence 1:50-1:200
Theoretical MW
38 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for DNAM-1/CD226 Antibody

  • CD226 antigenplatelet and T cell activation antigen 1
  • CD226 molecule
  • CD226
  • DNAM1
  • DNAM-1
  • DNAM1adhesion glycoprotein
  • DNAM-1DNAX accessory molecule-1
  • DNAX accessory molecule 1
  • PTA1
  • T lineage-specific activation antigen 1 antigen
  • TLiSA1

Background

CD226 is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. CD226 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. CD226 is also expressed by a subset of CD3 positive thymocytes. This antibody is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional DNAM-1/CD226 Products

Bioinformatics Tool for DNAM-1/CD226 Antibody (NBP1-00745)

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Diseases for DNAM-1/CD226 Antibody (NBP1-00745)

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Bioinformatics

Gene Symbol CD226
Entrez
Uniprot