DMAP1 Antibody

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP2-03983
    • Availability
      Product Discontinued

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DMAP1 Antibody Summary

Immunogen
Amino acid 445-467 of human DMAP1 protein was used as the immunogen.
Epitope
TPNSRKRRESASSSSSVKKAKKP
Clonality
Polyclonal
Host
Rabbit
Gene
DMAP1
Purity
Unpurified
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Applications/Dilutions

Dilutions
  • ELISA 1:100-1:1000

Reactivity Notes

The amino acid sequence used as immunogen is 100% homologous in human (isoform CRA_a and CRA_c), chimpanzee, cow, dog, mouse and rat, 91% homologous in pufferfish.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.1 ml crude whole Rabbit sera with 50% Glycerol
Preservative
0.025% Sodium Azide
Purity
Unpurified

Alternate Names for DMAP1 Antibody

  • DNA methyltransferase 1 associated protein 1
  • DNA methyltransferase 1-associated protein 1
  • DNMAP1DNMT1-associated protein 1
  • DNMT1 associated protein 1
  • DNMTAP1
  • EAF2
  • FLJ11543
  • KIAA1425DKFZp686L09142
  • MEAF2
  • SWC4

Background

DNA methyltransferase 1-associated protein 1 (DMAP1) is involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The protein also specifically potentiates DAXX-mediated repression of glucocorticoid receptor-dependent transcription. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. DMAP1 is found in a wide variety of living organisms from yeasts to humans. The human DMAP1 gene is localized on chromosome 1p34.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol DMAP1
Uniprot