DMAP1 Antibody (1A5)

Images

 
Western Blot: DMAP1 Antibody (1A5) [H00055929-M02] - Analysis of DMAP1 expression in transfected 293T cell line by DMAP1 monoclonal antibody (M02), clone 1A5.Lane 1: DMAP1 transfected lysate(53 KDa).Lane 2: ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
1A5
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

DMAP1 Antibody (1A5) Summary

Immunogen
DMAP1 (NP_061973, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag.MATGADVRDILELGGPEGDAASGTISKKDIINPDKKKSKKSSETLTFKRPEGMHREVYALLYSDKKDAPPLLPSDTGQGYRTVKAKLGSKKVRPWKWMPF
Specificity
DMAP1 - DNA methyltransferase 1 associated protein 1
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
DMAP1
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA
Application Notes
Antibody reactive against transfected lysate for western blot. It has also been used for ELISA.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for DMAP1 Antibody (1A5)

  • DNA methyltransferase 1 associated protein 1
  • DNA methyltransferase 1-associated protein 1
  • DNMAP1DNMT1-associated protein 1
  • DNMT1 associated protein 1
  • DNMTAP1
  • EAF2
  • FLJ11543
  • KIAA1425DKFZp686L09142
  • MEAF2
  • SWC4

Background

This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol DMAP1
Entrez
OMIM
Uniprot