Rat Dkk-1 ELISA Kit (Colorimetric)

ELISA: Rat Dkk-1 ELISA Kit (Colorimetric) [NBP2-61303] - These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Product Discontinued

Rat Dkk-1 ELISA Kit (Colorimetric) Summary

• Standard Curve Range: 39.1 - 1250 pg/ml
• Sensitivity: 26.1 pg/ml
• Assay Type: Sandwich ELISA
• Inter-Assay: Mean 9.9%
• Intra-Assay: Mean 8.0%
• Spike Recovery: F12K + 10% FBS
  Low - 88%
  Medium - 96%
  High - 109%
  Serum Low - 77
  Medium - 101%
  High - 116%
  EDTA Plasma
  Low - 92%
  Medium - 98%
  High - 98%
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: DKK1

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Store at 4°C.

Alternate Names for Rat Dkk-1 ELISA Kit (Colorimetric)

• dickkopf (Xenopus laevis) homolog 1
• dickkopf homolog 1 (Xenopus laevis)
• dickkopf related protein-1
• Dickkopf-1
• dickkopf-related protein 1
• Dkk1
• Dkk-1
• hDkk-1
• SKdickkopf-1 like

Background

Dkk-1 (Dickkopf-1) is a secreted inhibitor of the canonical Wnt signaling pathway, which mediates a variety of cellular processes including the growth and development of osteoblasts. Dkk-1 disrupts the canonical pathway by binding to the LRP5/6 co-receptors, preventing interaction with Wnt, and facilitating the degradation of beta-catenin. Dkk-1 is overexpressed in multiple myeloma, increasing bone resorption and the appearance of osteolytic lesions characteristic of multiple myeloma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Publications for Dkk-1 ELISA Kit (NBP2-61303)(1)

Publication using NBP2-61303

• Mace M, Gravesen E, Nordholm A et al. The Calcified Vasculature in Chronic Kidney Disease Secretes Factors that Inhibit Bone Mineralization JBMR Plus 2022-03-01 [PMID: 35434452] (ELISA)

FAQs for Dkk-1 ELISA Kit (NBP2-61303). (Showing 1 - 1 of 1 FAQ).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: DKK1