Dihydrofolate Reductase/DHFR Antibody (3A11)

Images

 
Western Blot: Dihydrofolate reductase Antibody (3A11) [NBP1-47726] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Dihydrofolate reductase (Right lane) cDNA for 48 hrs and lysed. ...read more
Immunohistochemistry-Paraffin: Dihydrofolate reductase Antibody (3A11) [NBP1-47726] Staining of paraffin-embedded pancreas tissue using anti-Dihydrofolate reductase mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Dihydrofolate reductase Antibody (3A11) [NBP1-47726] - Staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-Dihydrofolate reductase mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Dihydrofolate reductase Antibody (3A11) [NBP1-47726] - Staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-Dihydrofolate reductase mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Dihydrofolate reductase Antibody (3A11) [NBP1-47726] - Staining of paraffin-embedded Adenocarcinoma of ovary tissue using anti-Dihydrofolate reductase mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Dihydrofolate reductase Antibody (3A11) [NBP1-47726] - Staining of paraffin-embedded breast tissue using anti-Dihydrofolate reductase mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Dihydrofolate reductase Antibody (3A11) [NBP1-47726] - Staining of paraffin-embedded Carcinoma of bladder tissue using anti-Dihydrofolate reductase mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Dihydrofolate reductase Antibody (3A11) [NBP1-47726] - Staining of paraffin-embedded Carcinoma of kidney tissue using anti-Dihydrofolate reductase mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Dihydrofolate reductase Antibody (3A11) [NBP1-47726] - Staining of paraffin-embedded Carcinoma of lung tissue using anti-Dihydrofolate reductase mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Dihydrofolate reductase Antibody (3A11) [NBP1-47726] - Staining of paraffin-embedded endometrium tissue using anti-Dihydrofolate reductase mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Dihydrofolate reductase Antibody (3A11) [NBP1-47726] - Staining of paraffin-embedded lung tissue using anti-Dihydrofolate reductase mouse monoclonal antibody.

Order Details


    • Catalog Number
      NBP1-47726
    • Availability
      Product Discontinued

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Dihydrofolate Reductase/DHFR Antibody (3A11) Summary

Immunogen
Protein expressed in 293T cell transfected with human DHFR expression vector
Specificity
This antibody is specific for Homo sapiens dihydrofolate reductase (DHFR).
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
DHFR
Purity
Immunogen affinity purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Dihydrofolate Reductase/DHFR Antibody (3A11)

  • DHFR
  • DHFRP1
  • Dihydrofolate Reductase
  • DYR
  • EC 1.5.1.3

Background

Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol DHFR
Entrez