Desmoglein-2 Antibody

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Western Blot: Desmoglein-2 Antibody [NBP1-51354] - Analysis of Dsg2 (V440) pAb in extracts from HeLa cells.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-51354
    • Availability
      Product Discontinued

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Desmoglein-2 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 408-456 of Human Dsg2.
Specificity
Dsg2 (V440) pAb detects endogenous levels of Dsg2 protein.
Clonality
Polyclonal
Host
Rabbit
Gene
DSG2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
Application Notes
Western blot (WB) analysis of Dsg2 (V440) pAb in extracts from HeLa cells.
Theoretical MW
140 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (approx. pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Desmoglein-2 Antibody

  • ARVC10
  • ARVD10
  • Cadherin family member 5
  • CDHF5
  • CDHF5MGC117034
  • CMD1BB
  • desmoglein 2
  • Desmoglein2
  • Desmoglein-2
  • DSG2
  • HDGC
  • MGC117036
  • MGC117037

Background

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 2 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol DSG2
Entrez