Desmin Antibody (4G1)

Images

 
Western Blot: Desmin Antibody (4G1) [NBP2-03539] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Desmin (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates ...read more
Immunohistochemistry-Paraffin: Desmin Antibody (4G1) [NBP2-03539] Staining of paraffin-embedded Human prostate tissue using anti-Desmin mouse monoclonal antibody.
Flow Cytometry: Desmin Antibody (4G1) [NBP2-03539] - HEK293T cells transfected with either overexpression plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-Desmin antibody, and then ...read more
Immunohistochemistry-Paraffin: Desmin Antibody (4G1) [NBP2-03539] - Staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-Desmin mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Desmin Antibody (4G1) [NBP2-03539] - Staining of paraffin-embedded Human endometrium tissue using anti-Desmin mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Desmin Antibody (4G1) [NBP2-03539] - Staining of paraffin-embedded Human lymph node tissue using anti-Desmin mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Desmin Antibody (4G1) [NBP2-03539] - Staining of paraffin-embedded Human lymphoma tissue using anti-Desmin mouse monoclonal antibody.

Product Details

Summary
Reactivity Hu, PmSpecies Glossary
Applications WB, Flow, IHC, IHC-P
Clone
4G1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Desmin Antibody (4G1) Summary

Immunogen
Human fragment corresponding to amino acids 104-400 of human DES (NP_001918) produced in E.coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
DES
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:200-500
  • Flow Cytometry 1:100
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:150

Reactivity Notes

Reacts with: Monkey

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Desmin Antibody (4G1)

  • CMD1I
  • CMD1IFLJ41013
  • CSM1
  • CSM2
  • DES
  • Desmin
  • FLJ12025
  • FLJ39719
  • FLJ41793
  • intermediate filament protein

Background

This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq].

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Blogs on Desmin.

Alpha-smooth muscle actin and the modulation of endothelial and epithelial cell biology
Actin is essential for a wide range of cell functions, ranging from cell division and chromatin remodeling to vesicle trafficking and maintenance of cellular structure. In fact, mislocalization of actin to cell junctions during development leads t...  Read full blog post.

Vimentin in Wound Healing
Vimentin is a fundamental 10 nm type III intermediate filament (IF) protein found in many mesenchymal and epithelia tissues, tissue culture cells, and developing neuronal and astrocytic precursor cells of the central nervous system. It frequently co-p...  Read full blog post.

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Bioinformatics

Gene Symbol DES
Entrez