delta Opioid R/OPRD1 Antibody

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Immunocytochemistry/ Immunofluorescence: delta Opioid R/OPRD1 Antibody [NB100-1622] - Transfected Cells

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-1622
    • Availability
      Product Discontinued

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delta Opioid R/OPRD1 Antibody Summary

Immunogen
Synthetic peptide: TACTPSDGPGGGAAA, corresponding to amino acids 358-372 of Rat Delta Opioid Receptor.
Localization
Multi pass membrane protein
Specificity
Delta Opioid Receptor
Clonality
Polyclonal
Host
Rabbit
Gene
OPRD1
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence 1:10-1:2000
Publications
Read Publications using NB100-1622.

Reactivity Notes

Expected to cross-react with Human (100% identity with immunogen) due to sequence homology.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
Whole antisera
Preservative
0.05% Sodium Azide
Purity
Unpurified

Alternate Names for delta Opioid R/OPRD1 Antibody

  • delta Opioid R
  • delta opioid receptor 1
  • delta-type opioid receptor
  • DOP
  • dOpioidR
  • DOR1
  • D-OR-1
  • DOR-1
  • OP1
  • opioid receptor, delta 1
  • OPRD
  • OPRD1

Background

This protein functions as an inhibitor for neurotransmittors release by reducing calcium ion currents and increasing potassium ion conductance. Jordan and Devi (1999) provided biochemical and pharmacologic evidence for the heterodimerization of 2 fully functional opioid receptors, kappa (OPRK1; 165196) and delta. This results in a new receptor that exhibits ligand binding and functional properties that are distinct from those of either receptor. Furthermore, the kappa-delta heterodimer synergistically binds highly selective agonists and potentiates signal transduction. Pharmacologic and electrophysiologic evidence indicates that opioid receptors are involved in the mechanism of heroin dependence. Thus, opioid receptors are appropriate candidate genes for case-control association studies of heroin dependence Xu et al. (2002).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for delta Opioid R/OPRD1 Antibody (NB100-1622)(3)

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

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Diseases for delta Opioid R/OPRD1 Antibody (NB100-1622)

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Bioinformatics

Gene Symbol OPRD1
Entrez
Uniprot