Dehydroepiandrosterone Antibody (BGN/1177/1122)

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Product Details

Summary
Product Discontinued
View other related Dehydroepiandrosterone Primary Antibodies

Order Details


    • Catalog Number
      NB100-62497
    • Availability
      Product Discontinued

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Dehydroepiandrosterone Antibody (BGN/1177/1122) Summary

Immunogen
DHEA-3-HS-BSA
Localization
Secreted
Specificity
This product was raised against Dehydroepiandrosterone (DHEA) but demonstrates greater reactivity with Dehydroepiandrosterone Sulfate (DHEAS):

DHEAS 100%
DHEA 17%
Progesterone 0.008%
Testosterone 0.004%

DHEA is the most abundant hormone in the human body and a precursor of all the sex hormones. It is synthesized principally in the adrenal glands and gonads from cholesterol, through conversion to pregnenolone and 17Alpha-Hydroxypregnenolone, by the action of P450 enzymes.

DHEA is mainly found in serum as the sulfated form Dehydroepiandrosterone Sulfate (DHEAS), produced through a reversible reaction catalysed by sulfotransferase in the adrenal glands, liver and small intestine.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100000-1:400000
Positive Control
Cytosolic Sulfotransferase 2A1/SULT2A1 Lysate (NBL1-16607)

Reactivity Notes

Broad. Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
2.7 mg/ml
Purity
Protein A purified

Alternate Names for Dehydroepiandrosterone Antibody (BGN/1177/1122)

  • 3beta-hydroxyandrost-5-en-17-one
  • 5-androsten-3beta-ol-17-one
  • androstenolone
  • prasterone

Background

Dehydroepiandrosterone (DHEA) is a major secretory product of the human adrenal cortex during intrauterine development as well as during adulthood. DHEA circulates in the bloodstream as DHEA-sulfate (DHEAS). DHEA has been implicated in a wide range of physiological roles including aging, immunology, learning and memory and obesity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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