Dectin-2/CLEC6A Antibody (D2.11E-4) [DyLight 488]

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Product Details

Summary
Product Discontinued
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    • Catalog Number
      NB100-65409G
    • Availability
      Product Discontinued

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Dectin-2/CLEC6A Antibody (D2.11E-4) [DyLight 488] Summary

Immunogen
Dectin-2 (extracellular domain) Fc Fusion protein.
Specificity
NB100-65409 recognizes mouse DC-associated C-type lectin-2 (Dectin-2), a type II transmembrane protein that is a member of the C-type lectin superfamily. In mouse, dectin-2 is predominantly expressed on tissue macrophages and some dendritic cells. Clone D2.11E4 does not stain brain microglia or meningeal macrophages. Significant expression of Dectin-2 has been reported on macrophages in the red pulp and marginal zones of the spleen, kupffer cells in the liver and alveolar macrophages in the lung. Peripheral blood monocytes express low levels of dectin-2 but transient up-regulation of expression has been demonstrated on monocytes at sites of inflammation. The function of dectin-2 has not been fully determined but studies suggest a possible role in immune-surveillance.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
CLEC6A
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Frozen

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Dectin-2/CLEC6A Antibody (D2.11E-4) [DyLight 488]

  • CLEC4N
  • CLEC6A
  • CLECSF10
  • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 10
  • C-type lectin domain family 6 member A
  • C-type lectin domain family 6, member A
  • C-type lectin superfamily member 10
  • DC-associated C-type lectin 2
  • dectin 2
  • Dectin2
  • Dectin-2
  • Dendritic cell-associated C-type lectin 2

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CLEC6A
Entrez