DDR1 RNAi

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications RNAi, RNAi SP

Order Details

DDR1 RNAi Summary

Specificity
discoidin domain receptor family, member 1 (DDR1), mRNA
Gene
DDR1

Applications/Dilutions

Application Notes
This RNAi causes protein knockdown.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for DDR1 RNAi

  • CAK
  • CD167 antigen-like family member A
  • CD167a antigen
  • CD167a
  • DDR
  • DDR1
  • discoidin domain receptor family, member 1
  • discoidin domain receptor tyrosine kinase 1
  • Discoidin receptor tyrosine kinase
  • EC 2.7.10
  • EC 2.7.10.1
  • EDDR1
  • ENTRK4
  • Epithelial discoidin domain receptor 1
  • HGK2
  • MCK10
  • MCK-10
  • NTRK4
  • Protein-tyrosine kinase 3A
  • PTK3A protein tyrosine kinase 3A
  • PTK3A
  • receptor, type 4
  • RTK6
  • TRK E
  • TrkE

Background

Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene.  The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo.  Chimera RNAi has many advantages over the conventional siRNAs.  First, it has been demonstrated to have reliable knock-down for over 10,000 human genes.  Because the human genome is composed of an intricate, genetic network, chimera RNAi's unique design has successfully obviated the off-target effects including microRNA-based influence.  Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected.  Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. RNAi are guaranteed for 3 months from date of receipt.

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FAQs for DDR1 RNAi (H00000780-R08). (Showing 1 - 1 of 1 FAQ).

  1. I was wondering if you offer, or are planning on offering, any antibodies targeted to specific phosphorylation sites on the receptor tyrosine kinase DDR1.
    • At this time we do not offer and DDR1 antibodies specific for certain phosphorylation states.

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Blogs on DDR1.

Further unraveling the role of gamma H2AX in DNA damage response
Our genome experiences a moderate amount of DNA damage in our cells on a daily basis.  This DNA damage can be in response to external environmental factors, or be a result of our internal metabolic processes going awry.  While normal rates of DNA ...  Read full blog post.

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Bioinformatics

Gene Symbol DDR1
Entrez