DDR1 Antibody

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Immunohistochemistry: DDR1 Antibody [NB110-55506] - Analysis of anti-DDR1 antibody with human placenta.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB110-55506
    • Availability
      Product Discontinued

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DDR1 Antibody Summary

Immunogen
Synthetic 16 amino acid peptide from internal region of human DDR1.
Epitope
Internal
Specificity
Human DDR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Porcine (94%), Bovine (94%), Rabbit (94%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
DDR1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 2 ug/ml
Positive Control
DDR1 Lysate (NBL1-09777)

Reactivity Notes

Chimpanzee, Gorilla, Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Elephant (100%), Monkey (88%), Panda (88%), Canine (81%), Bat (81%), Opossum (81%), Platypus (81%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for DDR1 Antibody

  • CAK
  • CD167 antigen-like family member A
  • CD167a antigen
  • CD167a
  • DDR
  • DDR1
  • discoidin domain receptor family, member 1
  • discoidin domain receptor tyrosine kinase 1
  • Discoidin receptor tyrosine kinase
  • EC 2.7.10
  • EC 2.7.10.1
  • EDDR1
  • ENTRK4
  • Epithelial discoidin domain receptor 1
  • HGK2
  • MCK10
  • MCK-10
  • NTRK4
  • Protein-tyrosine kinase 3A
  • PTK3A protein tyrosine kinase 3A
  • PTK3A
  • receptor, type 4
  • RTK6
  • TRK E
  • TrkE

Background

DDR1 is a DDR/TKT type protein kinase. DDR1 is activated by various types of collagen, including types I through IV. Binding of collagen to DDR1 protein results in autophosphorylation and a delayed but sustained tyrosine kinase activation. DDR1 may function in cell-to-cell interaction or recognition. At least three mRNA variants, resulting in different protein isoforms of 875, 913 and 919 amino acids, have been reported. DDR1 protein has been shown to be over expressed in human breast, ovarian, esophageal and pediatric brain tumors.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for DDR1 Antibody (NB110-55506). (Showing 1 - 1 of 1 FAQ).

  1. I was wondering if you offer, or are planning on offering, any antibodies targeted to specific phosphorylation sites on the receptor tyrosine kinase DDR1.
    • At this time we do not offer and DDR1 antibodies specific for certain phosphorylation states.

Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for DDR1 Antibody (NB110-55506)

Discover related pathways, diseases and genes to DDR1 Antibody (NB110-55506). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for DDR1 Antibody (NB110-55506)

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Pathways for DDR1 Antibody (NB110-55506)

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Blogs on DDR1.

Further unraveling the role of gamma H2AX in DNA damage response
Our genome experiences a moderate amount of DNA damage in our cells on a daily basis.  This DNA damage can be in response to external environmental factors, or be a result of our internal metabolic processes going awry.  While normal rates of DNA ...  Read full blog post.

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Bioinformatics

Gene Symbol DDR1
Entrez