DC-SIGN/CD209 Antibody

Images

 
Western Blot: DC-SIGN/CD209 Antibody [H00030835-B01P] - Analysis of CD209 expression in transfected 293T cell line by CD209 polyclonal antibody. Lane 1: CD209 transfected lysate(44.44 KDa). Lane 2: Non-transfected ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      H00030835-B01P
    • Availability
      Product Discontinued

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DC-SIGN/CD209 Antibody Summary

Immunogen
CD209 (NP_066978, 1 a.a. ~ 404 a.a) full-length human protein.MSDSKEPRLQQLGLLEEEQLRGLGFRQTRGYKSLAGCLGHGPLVLQLLSFTLLAGLLVQVSKVPSSISQEQSRQDAIYQNLTQLKAAVGELSEKSKLQEIYQELTQLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTWLKAAVGELPEKSKMQEIYQELTRLKAAVGELPEKSKQQEIYQELTRLKAAVGELPEKSKQQEIYQELTRLKAAVGELPEKSKQQEIYQELTQLKAAVERLCHP
Marker
Dendritic Cell Marker
Specificity
CD209 - CD209 antigen,
Clonality
Polyclonal
Host
Mouse
Gene
CD209
Purity
IgG purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA
Application Notes
Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for DC-SIGN/CD209 Antibody

  • CD209 antigendendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbingnon-integrin
  • CD209 molecule
  • CD209
  • CDSIGNHIV gpl20-binding protein
  • CLEC4L
  • CLEC4LC-type lectin domain family 4 member L
  • DCSIGN
  • DC-SIGN
  • DC-SIGN1
  • DC-SIGN1C-type lectin domain family 4, member L
  • DC-SIGNMGC129965
  • Dendritic cell-specific ICAM-3-grabbing non-integrin 1

Background

The phylogenetically ancient innate immune system governs the initial detection of pathogens and stimulates the first line of host defense. Recognition of pathogens is mediated by phagocytic cells through germline-encoded receptors, known as 'pattern recognition receptors,' which detect pathogen-associated molecular patterns that are characteristic products of microbial physiology. This initial interaction is then translated into a set of endogenous signals that ultimately lead to the induction of the adaptive immune response. The C-type lectin receptors are involved in the primary interface between host and pathogens. Two prototypic members of the C-type lectin-receptor family act as both cell-adhesion receptors and pathogen-recognition receptors: CD209 and its close relative CD209L (MIM 605872) (Barreiro et al., 2005 [PubMed 16252244]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Diseases for DC-SIGN/CD209 Antibody (H00030835-B01P)

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Bioinformatics

Gene Symbol CD209
Entrez
Uniprot