DC-SIGN/CD209 Antibody (MR-1)

Images

 
Flow Cytometry: DC-SIGN/CD209 Antibody (MR-1) [NB100-64318] - Staining of CD209 transfected K562 cells with MOUSE ANTI HUMAN CD209

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, Func, ICC/IF
Clone
MR-1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1.0 mg/ml

DC-SIGN/CD209 Antibody (MR-1) Summary

Immunogen
Immature myeloid monocyte-derived dendritic cells (MDDCs)
Marker
Dendritic Cell Marker
Specificity
NB100-64318 recognizes human DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN)
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CD209
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
  • Functional
  • Immunocytochemistry/Immunofluorescence 1:10-1:2000
Application Notes
Clone MR-1 is reported to partially block the functional activity of DC-SIGN
Positive Control
DC-SIGN/CD209 Lysate (NBL1-08921)

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
No buffer
Preservative
No Preservative
Concentration
1.0 mg/ml
Purity
Protein G purified

Alternate Names for DC-SIGN/CD209 Antibody (MR-1)

  • CD209 antigendendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbingnon-integrin
  • CD209 molecule
  • CD209
  • CDSIGNHIV gpl20-binding protein
  • CLEC4L
  • CLEC4LC-type lectin domain family 4 member L
  • DCSIGN
  • DC-SIGN
  • DC-SIGN1
  • DC-SIGN1C-type lectin domain family 4, member L
  • DC-SIGNMGC129965
  • Dendritic cell-specific ICAM-3-grabbing non-integrin 1

Background

SIGN R1 is a specific marker for the identification of macrophage subpopulations present in the marginal zone of spleen (the so-called marginal zone macrophages (MZM)), in the lymph node medulla, and in some strains, in the peritoneal cavity. MZM of the spleen are involved in the clearance of polysaccharides. Mouse SIGN R1 is a C type lectin, like DC SIGN which is expressed on Human dendritic cells (DCs). However, mouse SIGN R1 itself is not expressed on DCs. SIGN R1 exists in an aggregated form, resistant to dissociation into monomers upon boiling in SDS under reducing conditions. SIGN R1 mediates the uptake of encapsulated organisms and may be an important mediator for the uptake of microbes in both spleen and lymph node, particularly through the recognition of microbial polysaccharides.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-92684
Species: Hu, Mu, Rt, Po, Bv
Applications: WB, ICC/IF
MAB162
Species: Hu
Applications: Flow, AdBlk, CyTOF-ready
NBP2-46010
Species: Hu, Ca, Mk
Applications: WB, IHC, IF
NB100-524
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP, Flow-IC
AF-386-PB
Species: Hu
Applications: WB, Flow, CyTOF-ready, ICC
H00003117-M01
Species: Hu
Applications: WB, ELISA, PLA
NBP1-19371
Species: Hu, Mu, Rt, Ca, Rb
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
MAB1774
Species: Hu
Applications: Flow, CyTOF-ready, ICC
NBP1-88968
Species: Hu
Applications: WB, IHC, IHC-P
NBP2-25208
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
MAB140
Species: Hu
Applications: Flow, IHC, CyTOF-ready, ELISA(Cap), ELISA(Det), Neut, ELISA(Sta)
DDX0191P-100
Species: Hu, Mu, Ca, Fe, Sh
Applications: ICC/IF, IHC, IHC-P
NB100-56566
Species: Hu, Mu, Rt
Applications: WB, ChIP, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, In vitro, CyTOF-ready, Flow-CS, Flow-IC
NB100-683
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP

Publications for DC-SIGN/CD209 Antibody (NB100-64318) (0)

There are no publications for DC-SIGN/CD209 Antibody (NB100-64318).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for DC-SIGN/CD209 Antibody (NB100-64318) (0)

There are no reviews for DC-SIGN/CD209 Antibody (NB100-64318). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

ICC/IF Video Protocol

FAQs for DC-SIGN/CD209 Antibody (NB100-64318) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Additional DC-SIGN/CD209 Products

Bioinformatics Tool for DC-SIGN/CD209 Antibody (NB100-64318)

Discover related pathways, diseases and genes to DC-SIGN/CD209 Antibody (NB100-64318). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for DC-SIGN/CD209 Antibody (NB100-64318)

Discover more about diseases related to DC-SIGN/CD209 Antibody (NB100-64318).
 

Pathways for DC-SIGN/CD209 Antibody (NB100-64318)

View related products by pathway.

PTMs for DC-SIGN/CD209 Antibody (NB100-64318)

Learn more about PTMs related to DC-SIGN/CD209 Antibody (NB100-64318).
 

Research Areas for DC-SIGN/CD209 Antibody (NB100-64318)

Find related products by research area.

Blogs on DC-SIGN/CD209

There are no specific blogs for DC-SIGN/CD209, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our DC-SIGN/CD209 Antibody (MR-1) and receive a gift card or discount.

Bioinformatics

Gene Symbol CD209
Entrez
Uniprot