DC-SIGN/CD209 Antibody (eB-h209)

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Flow Cytometry: DC-SIGN/CD209 Antibody (eB-h209) [NBP1-43327] - Analysis using the PE conjugate of NBP1-43327. Analysis of cultured human dendritic cells and peripheral blood leukocytes using DC-SIGN PE conjugage. This ...read more
Flow Cytometry: DC-SIGN/CD209 Antibody (eB-h209) [NBP1-43327] - Staining of human monocyte-derived immature dendritic cells with 0.5 ug of Rat IgG2a K Isotype Control Purified (open histogram) or 0.5 ug of Anti-Human ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-43327
    • Availability
      Product Discontinued

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DC-SIGN/CD209 Antibody (eB-h209) Summary

Immunogen
The immunogen for this antibody was CD209.
Marker
Dendritic Cell Marker
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Rat
Gene
CD209
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
  • Immunoprecipitation 1:10-1:500
Application Notes
The eB-h209 antibody has been tested by flow cytometric analysis of cultured human dendritic cells and peripheral blood leukocytes. This can be used at less than or equal to 1 ug per test. Cell number should be determined empirically but can range from 10^5to 10^8cells/test.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Aqueous, may contain carrier protein/stabilizer.
Preservative
0.09% Sodium Azide
Purity
Protein A or G purified

Alternate Names for DC-SIGN/CD209 Antibody (eB-h209)

  • CD209 antigendendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbingnon-integrin
  • CD209 molecule
  • CD209
  • CDSIGNHIV gpl20-binding protein
  • CLEC4L
  • CLEC4LC-type lectin domain family 4 member L
  • DCSIGN
  • DC-SIGN
  • DC-SIGN1
  • DC-SIGN1C-type lectin domain family 4, member L
  • DC-SIGNMGC129965
  • Dendritic cell-specific ICAM-3-grabbing non-integrin 1

Background

The eB-h209 monoclonal antibody reacts with human CD209, also known as DC-SIGN, a 44 kDa type II transmembrane protein. DC-SIGN contains a C-type lectin binding domain and binds ICAM-3, ICAM-2, and HIV virus. Human dendritic cells preferentially express DC-SIGN. It has been postulated that DC-SIGN serves as a receptor for capture, trafficking, and transmission of HIV to T cells and supports primary immune response. eB-h209 was developed against a C-terminal peptide of human DC-SIGN.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CD209
Entrez