| Reactivity | HuSpecies Glossary |
| Applications | Flow |
| Clone | 406288 |
| Clonality | Monoclonal |
| Host | Mouse |
| Conjugate | Alexa Fluor 594 |
| Concentration | Please see the vial label for concentration. If unlisted please contact technical services. |
| Conjugate | Catalog # | Availability | Size | Price |
|---|---|---|---|---|
| Alexa Fluor 350 | IC5240U-100UG | |||
| Alexa Fluor 405 | IC5240V-100UG | |||
| Alexa Fluor 488 | IC5240G-100UG | |||
| Alexa Fluor 647 | IC5240R-100UG | |||
| Alexa Fluor 700 | IC5240N-100UG | |||
| Alexa Fluor 750 | IC5240S-100UG | |||
| Phycoerythrin | IC5240P | |||
| Unconjugated | MAB5240 | |||
| Immunogen | Human Dap12 synthetic peptide QGQRSDVYSDLNTQRPYYK Accession # O43914 |
| Specificity | Detects human DAP12 in Western blots. |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Host | Mouse |
| Gene | TYROBP |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Dilutions |
|
| Application Notes | Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells. |
| Storage | Store the unopened product at 2 - 8 °C. Do not use past expiration date. |
| Buffer | Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide. |
| Preservative | 0.09% Sodium Azide |
| Concentration | Please see the vial label for concentration. If unlisted please contact technical services. |
DAP12, also known as TYROBP and KARAP, is a transmembrane protein that functions as a signal transduction adaptor molecule. DAP12 is expressed as a disulfide-linked homodimer that associates with a variety of receptors on NK and myeloid cells. Complex formation is mediated by intramembrane ionic interaction between an aspartic acid residue in DAP12 and a lysine residue in the partnered receptor. Ligation of these receptors can trigger either cell activation or inhibition through the ITAM sequence in DAP12, resulting in activation of Src family tyrosine kinases. Human and mouse DAP12 share 73% amino acid sequence identity.
![DAP12 Antibody (406288) [Alexa Fluor® 594]](/sites/all/modules/enterprise-tech/et_datasheets/images/novus_guarantee.png "DAP12 Antibody (406288) [Alexa Fluor® 594]")
Secondary Antibodies |
Isotype Controls |
| Alexa Fluor 350 | IC5240U | |
| Alexa Fluor 405 | IC5240V | |
| Alexa Fluor 488 | IC5240G | |
| Alexa Fluor 594 | IC5240T | |
| Alexa Fluor 647 | IC5240R | |
| Alexa Fluor 700 | IC5240N | |
| Alexa Fluor 750 | IC5240S | |
| Phycoerythrin | IC5240P |
Diseases for DAP12 Antibody (IC5240T)Discover more about diseases related to DAP12 Antibody (IC5240T).
| Pathways for DAP12 Antibody (IC5240T)View related products by pathway.
|
PTMs for DAP12 Antibody (IC5240T)Learn more about PTMs related to DAP12 Antibody (IC5240T).
|
The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.
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