Cytokeratin 18 Antibody (CY-90)

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Product Details

Summary
Product Discontinued
View other related Cytokeratin 18 Primary Antibodies

Order Details


    • Catalog Number
      NB120-17151
    • Availability
      Product Discontinued

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Cytokeratin 18 Antibody (CY-90) Summary

Immunogen
Tissue / cell preparation (human epidermal carcinoma and MCF-7 human breast cancer allcells).
Localization
Cytoplasmic
Marker
Epithelial Marker
Specificity
Cytokeratin 18 (CY-90)
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
KRT18
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
IHC-P: 1/25 - 1/50. We suggest an incubation period of 30 minutes at room temperature. Proteolytic digestion may be required in some paraffin embedded tissue sections.Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user.
Positive Control
Cytokeratin 18 Lysate (NBL1-12385)

Reactivity Notes

Cross-reacts with Human.Not yet tested in other species.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Ascites
Preservative
Sodium Azide
Purity
Unpurified

Alternate Names for Cytokeratin 18 Antibody (CY-90)

  • Cell proliferation-inducing gene 46 protein
  • cell proliferation-inducing protein 46
  • CK-18
  • CYK18
  • Cytokeratin 18
  • cytokeratin-18
  • K18
  • Keratin 18
  • keratin, type I cytoskeletal 18
  • keratin-18
  • KRT18

Background

This antibody recognizes keratin polypeptide of 45 kD. In normal tissues, it reacts with a large number of epithelial cell types, including ductal and glandular epithelia. This antibody does not react with squamous epithelia. Most of the adenocarcinomas, basal cell carcinomas and benign and malignant epithelial lesions stain with this antibody.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for Cytokeratin 18 Antibody (NB120-17151)

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Blogs on Cytokeratin 18.

Cytokeratin 18 - A Intermediate Filament Cyotskeletal Component
Keratins, also called cytokeratins, are a family of filamentous structural proteins that form the intermediate filaments within epithelial cells. Keratins are differentially expressed depending on both the epithelial cell origin and degree of differen...  Read full blog post.

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Bioinformatics

Gene Symbol KRT18
Entrez