Cytokeratin 18 Antibody (1G8)

Images

 
Western Blot: Cytokeratin 18 Antibody (1G8) [H00003875-M03] - Analysis of KRT18 expression in Hela S3 NE (Cat # L013V3).
Immunocytochemistry/ Immunofluorescence: Cytokeratin 18 Antibody (1G8) [H00003875-M03] - Analysis of monoclonal antibody to KRT18 on HeLa cell. Antibody concentration 10 ug/ml
Sandwich ELISA: Cytokeratin 18 Antibody (1G8) [H00003875-M03] - Detection limit for recombinant GST tagged KRT18 is approximately 3ng/ml as a capture antibody.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      H00003875-M03
    • Availability
      Product Discontinued

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Cytokeratin 18 Antibody (1G8) Summary

Immunogen
KRT18 (AAH20982, 1 a.a. - 430 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MSFTTRSTFSTNYRSLGSVQAPSYGARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGSGGLATGIAGGLAGMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQKTTTRRIVDGKVVSETNDTKVLRH
Marker
Epithelial Marker
Specificity
keratin 18
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
KRT18
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Immunocytochemistry/Immunofluorescence
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IF and ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Cytokeratin 18 Antibody (1G8)

  • Cell proliferation-inducing gene 46 protein
  • cell proliferation-inducing protein 46
  • CK-18
  • CYK18
  • Cytokeratin 18
  • cytokeratin-18
  • K18
  • Keratin 18
  • keratin, type I cytoskeletal 18
  • keratin-18
  • KRT18

Background

KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics Tool for Cytokeratin 18 Antibody (H00003875-M03)

Discover related pathways, diseases and genes to Cytokeratin 18 Antibody (H00003875-M03). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Research Areas for Cytokeratin 18 Antibody (H00003875-M03)

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Blogs on Cytokeratin 18.

Cytokeratin 18 - A Intermediate Filament Cyotskeletal Component
Keratins, also called cytokeratins, are a family of filamentous structural proteins that form the intermediate filaments within epithelial cells. Keratins are differentially expressed depending on both the epithelial cell origin and degree of differen...  Read full blog post.

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Bioinformatics

Gene Symbol KRT18
Entrez
OMIM
Uniprot