Cytokeratin 1/10 Antibody (KRT10/1990R) [DyLight 350]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications Flow, ICC/IF, IHC, IHC-P
Clone
KRT10/1990R
Clonality
Monoclonal
Host
Rabbit
Conjugate
DyLight 350

Order Details

Cytokeratin 1/10 Antibody (KRT10/1990R) [DyLight 350] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Skin extract of a human Psoriasis patient
Localization
Cytoplasmic
Specificity
This MAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
KRT10
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Cytokeratin 1/10 Antibody (KRT10/1990R) [DyLight 350]

  • 67 kDa cytokeratin
  • CK 1
  • CK 10
  • CK1
  • CK10
  • Cytokeratin 10
  • Cytokeratin1
  • Cytokeratin10
  • EHK 1
  • EHK1
  • EPPK
  • Hair Alpha Protein
  • K1
  • k10
  • Keratin 1 (epidermolytic hyperkeratosis)
  • Keratin 1
  • Keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris)
  • Keratin 10
  • Keratin type I cytoskeletal 10
  • Keratin Type II Cytoskeletal 1
  • Keratin1
  • Keratin10
  • KPP
  • KRT 1
  • Krt 10
  • KRT1
  • KRT10
  • KRT1A
  • KRTA
  • NEPPK

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for Cytokeratin 1/10 Antibody (NBP2-75768UV) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-75768AF350
Alexa Fluor 405 NBP2-75768AF405
Alexa Fluor 488 NBP2-75768AF488
Alexa Fluor 532 NBP2-75768AF532
Alexa Fluor 594 NBP2-75768AF594
Alexa Fluor 647 NBP2-75768AF647
Alexa Fluor 700 NBP2-75768AF700
Alexa Fluor 750 NBP2-75768AF750
Allophycocyanin NBP2-75768APC
Biotin NBP2-75768B
DyLight 350 NBP2-75768UV
DyLight 405 NBP2-75768V
DyLight 488 NBP2-75768G
DyLight 550 NBP2-75768R
DyLight 594 NBP2-75768DL594
DyLight 650 NBP2-75768C
DyLight 680 NBP2-75768FR
DyLight 755 NBP2-75768IR
FITC NBP2-75768F
HRP NBP2-75768H
Janelia Fluor 549 NBP2-75768JF549
Janelia Fluor 646 NBP2-75768JF646
PE NBP2-75768PE
PerCP NBP2-75768PCP

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Bioinformatics Tool for Cytokeratin 1/10 Antibody (NBP2-75768UV)

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Bioinformatics

Gene Symbol KRT10