CYP7B1 Antibody

Images

 
Immunohistochemistry-Paraffin: CYP7B1 Antibody [NB100-1338] - staining.

Product Details

Summary
Product Discontinued
View other related CYP7B1 Primary Antibodies

Order Details


    • Catalog Number
      NB100-1338
    • Availability
      Product Discontinued

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CYP7B1 Antibody Summary

Immunogen
Peptide with sequence C-YPDSDVLFRYKVKS corresponding to C-Terminus according to NP_004811.1.
Localization
Endoplasmic reticulum
Clonality
Polyclonal
Host
Goat
Gene
CYP7B1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 3 - 6 ug/ml
  • Peptide ELISA Detection limit 1:128000
Application Notes
WB: Preliminary experiments in human liver, kidney and prostate lysates gave no specific signal but low background. IHC-P: Human breast shows textured cytoplasm staining in ductal epithelial cells.
Publications
Read Publication using NB100-1338.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Human, Bovine.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for CYP7B1 Antibody

  • CBAS3
  • CP7B
  • Cytochrome P450 7B1
  • cytochrome P450, family 7, subfamily B, polypeptide 1
  • cytochrome P450, subfamily VIIB (oxysterol 7 alpha-hydroxylase), polypeptide 1,25-hydroxycholesterol 7-alpha-hydroxylase
  • EC 1.14.13.100
  • Oxysterol 7-alpha-hydroxylase
  • oxysterol 7alpha-hydroxylase
  • spastic paraplegia 5A (autosomal recessive)
  • SPG5A

Background

CYP7B1 is involved in the conversion of cholesterol to bile acids; the first (rate-limiting) step. Defects in CYP7B1 are a cause of neonatal giant cell hepatitis. Patients present severe cholestasis, cirrhosis and liver synthetic failure.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CYP7B1 Antibody (NB100-1338)(1)

Reviews for CYP7B1 Antibody (NB100-1338) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for CYP7B1 Antibody (NB100-1338)

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Bioinformatics

Gene Symbol CYP7B1
Entrez
Uniprot