CYP2A13 Antibody

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Western Blot: CYP2A13 Antibody [NB100-92424] - Western blot (WB) analyzes of CYP2A13 (N338) antibody in extracts from HeLa cells

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-92424
    • Availability
      Product Discontinued

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CYP2A13 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 306-360 of Human CYP2A13.
Specificity
CYP2A13 (N338) detects endogenous levels of CYP2A13 (N338) protein.
Clonality
Polyclonal
Host
Rabbit
Gene
CYP2A13
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunocytochemistry/Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50-1:200
Application Notes
Western blot (WB) analyzes of CYP2A13 (N338) pAb in extracts from HeLa cells
Theoretical MW
56 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

This antibody is reactive against Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CYP2A13 Antibody

  • CPAD
  • CYP2A
  • CYPIIA13
  • cytochrome P450 2A13
  • cytochrome P450, family 2, subfamily A, polypeptide 13
  • cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 13
  • EC 1.14.14.1

Background

The immunosuppressant cyclosporin A (CsA) forms a trimolecular complex with cyclophilin and calcineurins to inhibit calcineurin phosphatase activity. Cyclophilins are conserved, ubiquitous and abundant cytosolic peptidyl-prolyl cis-trans isomerases that accelerate the isomerization of XaaPro peptide bonds and the refolding of proteins. Human cyclophilin A (CyPA), an intracellular protein of 165 amino acids, is the target of the CsA and is encoded by a single unique gene conserved from yeast to humans. CyPA is involved in T cell differentiation and proliferation and is highly expressed in brain. CyPA is incorporated into the virion of the type 1 human immunodeficiency virus (HIV-1) via a direct interaction with the capsid domain of the viral Gag polyprotein and is crucial for efficient viral replication.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CYP2A13
Entrez