CYP24A1 Antibody

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Western Blot: CYP24A1 Antibody [NBP1-68880] - Titration: 0.2-1 ug/ml, Positive Control: MCF7 cell lysate.

Product Details

Summary
Product Discontinued
View other related CYP24A1 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-68880
    • Availability
      Product Discontinued

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CYP24A1 Antibody Summary

Immunogen
Synthetic peptides corresponding to CYP24A1 (cytochrome P450, family 24, subfamily A, polypeptide 1) The peptide sequence was selected from the C terminal of CYP24A1. Peptide sequence QVLGSSEDNFEDSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAE.
Clonality
Polyclonal
Host
Rabbit
Gene
CYP24A1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Application Notes
This is a rabbit polyclonal antibody against CYP24A1 and was validated on Western blot.
Theoretical MW
55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 2% Sucrose
Preservative
0.09% Sodium Azide
Purity
Immunogen affinity purified

Notes

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for CYP24A1 Antibody

  • 25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial
  • CP241
  • CYP241,25-alphadihydroxyvitamin D3 24-hydroxylase
  • Cytochrome P450 24A1
  • cytochrome P450, family 24, subfamily A, polypeptide 1,24-OHase
  • cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase)
  • Cytochrome P450-CC24
  • EC 1.14.13.n4
  • exo-mitochondrial protein
  • MGC126273
  • MGC126274
  • P450-CC24
  • vitamin D 24-hydroxylase
  • Vitamin D(3) 24-hydroxylase

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CYP24A1
Uniprot