Cyclophilin B Antibody (k2E2)

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Western Blot: Cyclophilin B Antibody (k2E2) [NBP1-04270] - Cell lysates of HepG2 (30ug) and HeLa (30ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human Cyclophilin B (1:1,000). Proteins ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
k2E2
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Cyclophilin B Antibody (k2E2) Summary

Immunogen
Recombinant human Cyclophilin B (26-216aa) purified from E. coli (NP_000933).
Specificity
Anti-human Cyclophilin B mAb, clone k2E2, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Cyclophilin B protein.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PPIB
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000-1:2000
  • ELISA 1:100-1:2000

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4) and 10% Glycerol
Preservative
0.02% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein G purified

Alternate Names for Cyclophilin B Antibody (k2E2)

  • Cyclophilin B
  • cyclophilin-like protein
  • CYPB
  • CYPBEC 5.2.1.8
  • CYP-S1
  • MGC2224
  • OI9MGC14109
  • peptidyl-prolyl cis-trans isomerase B
  • peptidylprolyl isomerase B (cyclophilin B)
  • PPIase B
  • PPIB
  • Rotamase B
  • S-cyclophilin
  • SCYLP

Background

Cyclophilin B (also known as PPIB, peptidylpropyl isomerase B) is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Cyclophilin B is necessary for the prolactin-induced proliferation, cell growth, and the nuclear retrotransport of prolactin.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PPIB
Entrez
Uniprot