Cyclin H Antibody

Images

 
Western Blot: Cyclin H Antibody [NB100-87007] - Detection of Human Cyclin H by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity ...read more

Product Details

Summary
Product Discontinued
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Independent Antibodies

       

Order Details


    • Catalog Number
      NB100-87007
    • Availability
      Product Discontinued

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Cyclin H Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 225 and 275 of human cyclin H using the numbering given in entry NP_001230.1 (GeneID 902).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CCNH
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunoprecipitation 2 - 5 ug/mg lysate
Application Notes
This antibody is not recommended for Western Blot analysis.
Positive Control
Cyclin H Lysate (NBL1-08883)

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Cyclin H Antibody

  • CAK
  • cyclin H
  • cyclin-dependent kinase-activating kinase complex subunit
  • cyclin-H
  • MO15-associated protein
  • p34CAK complex subunit
  • p37CDK-activating kinase complex subunit

Background

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CCNH
Entrez
Uniprot