Cyclin D2 Antibody (DCS-3.1 + DCS-5.2)

Product Discontinued

Cyclin D2 Antibody (DCS-3.1 + DCS-5.2) Summary

• Description: This product is a cocktail with two clones in it: DCS-3.1 and DCS-5.2
• Immunogen: Purified histidine-tagged human recombinant full length cyclin D2 protein
• Localization: Nuclear
• Specificity: Cyclin D2 (DCS-3.1 + DCS-5.2)
• Isotype: IgG2a/IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: CCND2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:10 - 1:1000
  • Immunofluorescence 1 - 2 ug/ml
  • Immunohistochemistry 1:10 - 1:500
  • Immunohistochemistry-Frozen 1:10 - 1:500
  • Immunohistochemistry-Paraffin 1:10 - 1:500
  • Western Blot 1:100 - 1:2000
• Control:

  Cyclin D2 Overexpression Lysate

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS (pH 7.4) and 0.2% BSA
• Preservative: 0.09% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Protein A purified

Alternate Names for Cyclin D2 Antibody (DCS-3.1 + DCS-5.2)

• CCND2
• Cyclin D2
• G1/S-specific cyclin D2
• G1/S-specific cyclin-D2
• KIAK0002
• MGC102758
• Vin1

Background

Cyclin D2 is a G1 cyclin required for G1 phase progression and is a strong candidate for a proto oncogene. Cyclin D2 can phosphorylate pRB when associated with cdk 4 and / or cdk 6.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CCND2
• Entrez:
  • 894(Human)
  • 12444(Mouse)
  • 64033(Rat)