CXCR3 Antibody

Images

 
Western Blot: CXCR3 Antibody [NBP1-00770] - Anaylsis of CXCR3 at 1:500 dilution. Lane 1 - HEK293T cell lysate, Lane 2 - sp2/0 cell lysate, Lane 3 - H9C2 lysate.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-00770
    • Availability
      Product Discontinued

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CXCR3 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 280-320 of Human CXCR-3.
Specificity
CXCR3 antibody detects endogenous levels of CXCR3 protein.
Clonality
Polyclonal
Host
Rabbit
Gene
CXCR3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
Theoretical MW
40 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CXCR3 Antibody

  • CD183 antigen
  • CD183
  • chemokine (C-X-C motif) receptor 3
  • chemokine (C-X-C) receptor 3
  • CKR-L2IP-10 receptor
  • CMKAR3
  • C-X-C chemokine receptor type 3
  • CXCR3
  • CXC-R3
  • CXCR-3
  • G protein-coupled receptor 9CD182
  • GPR9
  • GPR9Mig-R
  • Interferon-inducible protein 10 receptor
  • IP10 receptor
  • IP10-R
  • Mig receptor
  • MigR

Background

The CXC or a chemokine family is characterized by a pair of cysteine residues separated by a single amino acid and primarily functions as chemo-attractants for neutrophils. The CXC family includes IL-8, NAP-2, MSGA and stromal cell derived factor-1 or SDF-1. SDF-1 was originally described as a pre-B cell stimulatory factor, but has now been shown to function as a potent chemoattractant for T cells and monocytes but not neutrophils. Receptors for the CXC family are G protein-coupled, seven pass transmembrane domain proteins which include IL-8RA, IL-8RB, CXCR-3 and fusin (variously referred to as LESTR or CXCR-4). CXCR-3, also known as IP-10/Mig receptor, mediates Ca++ mobilization and chemotaxis in response to the CXC chemo-kines IP-10 and Mig. CXCR-3 is highly expressed in IL-2-activated T lymphocytes, but not in resting T lymphocytes, B lymphocytes, monocytes or granulocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CXCR3
Entrez
Uniprot