CXCR1/IL-8 RA Antibody

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Western Blot: CXCR1 Antibody [NBP1-33784] - 55 kDa CXCR1Rec.

Product Details

Summary
Product Discontinued
View other related CXCR1/IL-8 RA Primary Antibodies

Order Details


    • Catalog Number
      NBP1-33784
    • Availability
      Product Discontinued

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CXCR1/IL-8 RA Antibody Summary

Immunogen
Synthetic peptide corresponding to the N-terminal region of the mouse CXCR1 protein (Swiss-Prot Q810W6).
Localization
Cell Membrane
Specificity
This antibody detects a single 55 kDa band. The antibody does not cross react with other members of the CXCR family. The immunogen peptide was post synthesis modified to achieve the desired antigenicty and label CXCR1 protein.
Clonality
Polyclonal
Host
Goat
Gene
CXCR1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:200
  • Immunoprecipitation 1:250

Reactivity Notes

Cross-reacts with Mouse. Not yet tested in other species

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Tris/Glycine buffer pH 7.5-7.9, stabilizing protein, and glycerol
Preservative
0.02% Sodium Azide
Concentration
0.65 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CXCR1/IL-8 RA Antibody

  • CD128
  • CD181 antigen
  • CD181
  • CDw128aC-C
  • chemokine (C-X-C motif) receptor 1
  • CKR-1
  • CMKAR1
  • C-X-C chemokine receptor type 1
  • CXCR1
  • CXC-R1
  • CXCR-1
  • High affinity interleukin-8 receptor A
  • IL-8 receptor type 1
  • IL-8R A
  • IL8R1
  • IL8RA
  • IL-8RA
  • IL8RAC-C-CKR-1
  • IL8RBA
  • interleukin 8 receptor, alpha
  • interleukin-8 receptor type 1
  • interleukin-8 receptor type A

Background

CXCR1 is a 67-70 kD seven-transmembrane protein, also known as IL-8 receptor A (IL-8RA), CD181, and CDw128a. It is a CXC chemokine receptor belongs to G protein-coupled receptor (CPCR) family. CXCR1 is expressed as homodimer or heterodimer with CXCR2 and found on granulocytes, NK cells, subset of T lymphocytes, mast cells, monocytes, endothelial cells, megakarocytes, and oligodendrocytes. The expression level of CXCR1 on monocytes is lower that of CXCR2. CXCR1 mediates nurophil activation and chemotaxis, megakaryocytic proliferation, and angiogenesis via binding its ligands including IL-8(CXCL8), NAP-2(CXCL7), GCP-2(CXCL6), and GRO- alpha(CXCL1).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics Tool for CXCR1/IL-8 RA Antibody (NBP1-33784)

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Bioinformatics

Gene Symbol CXCR1
Entrez