Recombinant Mouse CXCL5 Protein

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-99339
    • Availability
      Product Discontinued

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Recombinant Mouse CXCL5 Protein Summary

Description
A recombinant protein corresponding to 93 amino acids of Mouse CXCL5

Amino Acid Sequence: APSSVIAATE LRCVCLTVTP KINPKLIANL EVIPAGPQCP TVEVIAKLKN QKEVCLDPEA PVIKKIIIQK ILGSDKKKAK RNALAVERTA SVQ
Preparation
Method
>97% SDS-PAGE
Details of Functionality
Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 10.0-100.0 ng/ml.
Source
E. coli
Protein/Peptide Type
Biologically Active Protein
Gene
CXCL5
Purity
>95%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
9.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20 to -80C. Avoid freeze-thaw cycles.
Buffer
Lyophilized from a sterile filtered solution containing 20 mM sodium phosphate buffer, pH 7.4 and 150 mM NaCl.
Concentration
Lyoph
Purity
>95%, by SDS-PAGE
Reconstitution Instructions
Reconstitute in sterile ddH2O to a concentration> 100 ug/ml. This solution can then be diluted into other aqueous buffers.

Alternate Names for Recombinant Mouse CXCL5 Protein

  • chemokine (C-X-C motif) ligand 5
  • C-X-C motif chemokine 5
  • ENA-78
  • ENA-78(1-78)
  • epithelial-derived neutrophil activating protein 78
  • epithelial-derived neutrophil-activating peptide 78
  • Epithelial-derived neutrophil-activating protein 78
  • Neutrophil-activating peptide ENA-78
  • neutrophil-activating protein 78
  • SCYB5ENA78
  • small inducible cytokine B5
  • small inducible cytokine subfamily B (Cys-X-Cys), member 5 (epithelial-derivedneutrophil-activating peptide 78)
  • Small-inducible cytokine B5

Background

Chemokine (C-X-C motif) ligand 5 (CXCL5) is a small cytokine belonging to the CXC chemokine family that is also known as epithelial-derived neutrophil-activating peptide 78 (ENA-78). It is produced following stimulation of cells with the inflammatory cytokines interleukin-1 or tumor necrosis factor-alpha. Expression of CXCL5 has also been observed in eosinophils, and can be inhibited with the type II interferon IFN-?. This chemokine stimulates the chemotaxis of neutrophils possesses angiogenic properties. It elicits these effects by interacting with the cell surface chemokine receptor CXCR2. The gene for CXCL5 is encoded on four exons and is located on human chromosome 4 amongst several other CXC chemokine genes. CXCL5 has been implicated in connective tissue remodelling. Epithelial Neutrophil-Activating Protein 78 Mouse Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 93 amino acids and having a molecular mass of 9.8kDa.The CXCL5 is purified by proprietary chromatographic techniques

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 2 years from date of receipt.

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Bioinformatics

Gene Symbol CXCL5