Recombinant Feline CXCL12/SDF-1 Protein

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-99333
    • Availability
      Product Discontinued

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Recombinant Feline CXCL12/SDF-1 Protein Summary

Description
A recombinant protein corresponding to 72 amino acids of Feline CXCL12/SDF-1

Amino Acid Sequence: KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRF KM
Preparation
Method
>97% SDS-PAGE
Details of Functionality
Biological Activity: The activity is determined by its ability to chemoattract human T cells at 10 - 75 ng/ml.
Results: 10 - 75 ng/ml
Protein/Peptide Type
Recombinant Protein
Gene
CXCL12
Purity
>90% SDS-PAGE
Endotoxin Note
<0.01 ng/ug

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Concentration
Lyoph
Purity
>90% SDS-PAGE
Reconstitution Instructions
Centrifuge prior to opening. Reconstitute with sterilized water to a final concentration of 0.1 mg/ml.

Notes

The purity of this protein is >95% pure by SDS-PAGE

Alternate Names for Recombinant Feline CXCL12/SDF-1 Protein

  • chemokine (C-X-C motif) ligand 12
  • C-X-C motif chemokine 12
  • CXCL12
  • hIRH
  • hSDF-1
  • Intercrine reduced in hepatomas
  • IRH
  • PBSF
  • PBSFSDF-1a
  • Pre-B cell growth-stimulating factor
  • SCYB12
  • SDF1
  • SDF-1
  • SDF1A
  • SDF1B
  • SDF1SDF-1b
  • stromal cell-derived factor 1
  • TLSF
  • TLSF-a
  • TLSF-b
  • TPAR1

Background

Stromal Derived Growth Factor-1beta (SDF-1beta), also called CXCL12, is one of two splice variants made by a wide variety of cells when stimulated by inflammatory cytokines such as, TNF, IL-1 or LPS. SDF-1Beta signals through the G protein-couple receptor, CXCR4, to recruit activated leukocytes. Human SDF-1Beta shares 100% identity to feline SDF-1Beta. Recombinant feline SDF-1beta is a non-glycosylated protein, comprised of 72 amino acids, with a molecular weight of 8.5 kDa.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol CXCL12
Entrez