CXCL10/IP-10/CRG-2 Antibody

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

CXCL10/IP-10/CRG-2 Antibody Summary

Immunogen
Recombinant human CXCL10/INP10 expressed in E. coli.
Specificity
CXCL10/INP10
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
CXCL10
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
Application Notes
Predicted molecular weight: 8.7 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user.
Positive Control
CXCL10/IP-10/CRG-2 Lysate (NBL1-09621)

Reactivity Notes

Cross-reacts with Human. Not yet tested in other species.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 5% Trehalose
Preservative
No Preservative
Concentration
1.0 mg/ml
Purity
Protein G purified

Alternate Names for CXCL10/IP-10/CRG-2 Antibody

  • C7
  • chemokine (C-X-C motif) ligand 10
  • CRG2
  • CRG-2
  • CXCL10
  • gIP-10
  • IFI10
  • INP10
  • IP-10
  • mob-1
  • SCYB10

Background

IP-10 is a member of the C-X-C, or alpha chemokine class. It does not contains the ELR domain immediately preceding the first cysteine residue near the amino terminus. Other chemokines in this group include mouse CRG, Mig, PBSF/SDF-1, and PF4. These chemokines act primarily as chemoattractants and activate monocytes, dendritic cells, T lymphocytes, natural killer cells, B lymphocytes, basophils, and eosinophils. IP-10 was originally identified as an IFN-gamma- inducible gene in monocytes, fibroblasts, and endothelial cells. IP-10 is a chemoattractant for activated T lymphocytes. It is a potent inhibitor of angiogenesis and displays a thymus-dependent antitumor effect. IP-10 is an approximately 8.7 kDa polypeptide of 78 amino acids. The precursor form of human IP-10 consists of 98 amino acids. To generate the mature IP-10, the precursor cleaves its 21 amino acid signal peptide. Human IP-10 shows 67% amino acid homology to mouse CRG-2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CXCL10
Entrez