CXCL10/IP-10/CRG-2 Antibody (6D4) [FITC]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, IA, ICC/IF, IHC, IHC-Fr
Clone
6D4
Clonality
Monoclonal
Host
Mouse
Conjugate
FITC
Concentration
0.1 mg/ml

CXCL10/IP-10/CRG-2 Antibody (6D4) [FITC] Summary

Immunogen
Recombinant human CXCL10/INP10
Localization
Secreted
Specificity
The reacts specifically with Human CXCL10/INP10
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
CXCL10
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • Flow Cytometry 1:10-1:1000
  • Immunoassay
  • Immunocytochemistry/Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
Publications
Read Publications using NBP1-60145.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS and 0.1% BSA
Preservative
0.05% Sodium Azide
Concentration
0.1 mg/ml
Purity
Protein A or G purified

Notes

Positive control: Acitvated plasmacytoid dendritic cells Negative control: Normal liver

Alternate Names for CXCL10/IP-10/CRG-2 Antibody (6D4) [FITC]

  • C7
  • chemokine (C-X-C motif) ligand 10
  • CRG2
  • CRG-2
  • CXCL10
  • gIP-10
  • IFI10
  • INP10
  • IP-10
  • mob-1
  • SCYB10

Background

The monoclonal antibody 6D4 recognizes human C-X-C motif chemokine 10 (IP-10), a protein of 98 amino acids. IP-10, also known as CXCL10, functions as ligand for the CXCR3 receptor. IP-10 belongs to the a-chemokine (C-X-C) family, which can be divided in two subfamilies: (1) potent chemoattractants for neutrophils, like IL-8 and (2) potent chemoattractants for lymphocytes, like the IFNg inducible protein (IP)-10. IP-10 is produced by a wide variety of cell types ranging from neutrophils, dendritic cells and monocytes to hepatocytes, endothelial cells and keratinocytes. The cytokine is reported to be involved in a scala of inflammatory pathologies such as HIV, encephalitis, cutaneous T cell lymphoma, chronic hepatitis, psoriasis and acute anterior uveitis. Various observations strongly suggest a role for the C-X-C chemokines IL-8 and IP-10 in the regulation of angiogenic activity in cancer and in idiopathic pulmonary fibrosis. Furthermore IP-10 is associated with acute rejection processes estimated by the predictive properties of urinary IP-10 expression for the short- and long-term graft function after kidney transplantation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CXCL10/IP-10/CRG-2 Antibody (NBP1-60145)(3)

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics Tool for CXCL10/IP-10/CRG-2 Antibody (NBP1-60145)

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Diseases for CXCL10/IP-10/CRG-2 Antibody (NBP1-60145)

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Bioinformatics

Gene Symbol CXCL10
Entrez