Cutaneous Lymphocyte Antigen (CLA) Antibody (HECA-452) [DyLight 650]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, Flow, IHC, IHC-Fr, IHC-P
Clone
HECA-452
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 650

Cutaneous Lymphocyte Antigen (CLA) Antibody (HECA-452) [DyLight 650] Summary

Immunogen
Human tonsil stroma
Specificity
Cutaneous Lymphocyte Antigen
Isotype
IgM Kappa
Clonality
Monoclonal
Host
Rat
Gene
SELPLG
Purity
IgM purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
IgM purified

Notes

CLA antibody clone HECA-452 is known to recognize the cutaneous lymphocyte-associated antigen / CLA which is a specialized glycosylated form of P-selectin glycoprotein ligand-1/PSGL-1. Besides lymphocytes, this clone has been shown to react with normal endometrium as well as breast cancer tissues (PMID 19625313 and 22970241). Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Cutaneous Lymphocyte Antigen (CLA) Antibody (HECA-452) [DyLight 650]

  • CD162 antigen
  • CD162
  • CLA
  • Cutaneous Lymphocyte-Associated Associated Antigen
  • P-selectin glycoprotein ligand 1
  • PSGL1
  • PSGL-1
  • Selectin P Ligand

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for Cutaneous Lymphocyte Antigen (CLA) Antibody (NB100-78039C)

Discover related pathways, diseases and genes to Cutaneous Lymphocyte Antigen (CLA) Antibody (NB100-78039C). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for Cutaneous Lymphocyte Antigen (CLA) Antibody (NB100-78039C)

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Pathways for Cutaneous Lymphocyte Antigen (CLA) Antibody (NB100-78039C)

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PTMs for Cutaneous Lymphocyte Antigen (CLA) Antibody (NB100-78039C)

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Research Areas for Cutaneous Lymphocyte Antigen (CLA) Antibody (NB100-78039C)

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Blogs on Cutaneous Lymphocyte Antigen (CLA).

CLA - guiding T-cells to sites of inflammation
T-cells infiltrating sites of inflammation of the skin typically express the cutaneous lymphocyte-associate antigen (CLA). This antigen is defined by the binding of the monoclonal CLA antibody HECA-452. The CLA antigen is a fucose-containing oligo...  Read full blog post.

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Bioinformatics

Gene Symbol SELPLG