CUGBP1 Antibody (3B1) [FITC]


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Product Details

Reactivity Hu, Mu, Rt, Po, Bv, Pm, RbSpecies Glossary
Applications WB, IHC, IHC-Fr, IHC-P
Please see the vial label for concentration. If unlisted please contact technical services.

CUGBP1 Antibody (3B1) [FITC] Summary

Full-length human CUGBP1 [UniProt# Q92879]
IgG1 Kappa
Protein G purified
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Packaging, Storage & Formulations

Store at 4C in the dark.
FITC (A=495, E=519)
0.05% Sodium Azide
Please see the vial label for concentration. If unlisted please contact technical services.
Protein G purified


Application Notes
This CUGBP1 antibody is useful for Immunocytochemistry/Immunofluorescence, Immunohistochemistry frozen and paraffin embedded sections and Western Blot where a band is observed at ~50 kDa. Nuclear staining can be seen in ICC/IF. Immunoprecipitation and Gel Super Shift Assays were reported in scientific literature.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
50 kDa

Alternate Names for CUGBP1 Antibody (3B1) [FITC]

  • BRUNOL250 kDa nuclear polyadenylated RNA-binding protein
  • bruno-like 2
  • Bruno-like protein 2
  • CUG RNA-binding protein
  • CUG triplet repeat, RNA binding protein 1
  • CUG triplet repeat, RNA-binding protein 1
  • CUG-BP- and ETR-3-like factor 1
  • CUGBP Elav-like family member 1
  • CUG-BP
  • CUGBP, Elav-like family member 1
  • CUGBP1CUG triplet repeat RNA-binding protein 1
  • Deadenylation factor CUG-BP
  • EDEN-BP homolog
  • embryo deadenylation element binding protein
  • Embryo deadenylation element-binding protein homolog
  • hNab50
  • NAB50CUG-BP1
  • nuclear polyadenylated RNA-binding protein, 50-kD
  • RNA-binding protein BRUNOL-2


CUGBP1 (CUG-binding protein 1) is a member of CELF (CUG-BP- and ETR-3-like factors) family of RNA-binding proteins that binds to a variety of mRNA cis-elements including UG-rich elements, GC-rich elements, GU-rich elements and AREs, and has been implicated in the regulation of mRNA alternative splicing as well as the control of mRNA translation and stability. CUGBP1 is ubiquitously expressed with localization in nucleus and cytoplasm as a component of an EIF2 complex which contains CELF1/CUGBP1, CALR, CALR3, EIF2S1, EIF2S2, HSP90B1 and HSPA5. CUGBP1 also associates with polysomes and interacts with HNRNPH1 and PARN. CUGBP1 was originally discovered as a protein which interacts with RNA CUG repeats that are expanded in patients with DM1 (myotonic dystrophy), which binds to 3'-untranslated region of the dystrophin myotonia protein kinase (DMPK) gene. However, CUGBP1 was later shown as multifunctional protein regulating many posttranscriptional processes including alternative splicing, deadenylation, mRNA decay, and translation. It has been involved in the processes of development (embryonic and cardiac), differentiation (skeletal muscle and adipose tissue), germ cell formation, tumorigenesis (breast cancer, leukemia etc) and deterioration of certain tumors as well.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies


Isotype Controls

Other Available Formats

Allophycocyanin Labeled NB200-316APC
DyLight 350 Labeled NB200-316UV
DyLight 405 Labeled NB200-316V
DyLight 405LS Labeled NB200-316V3
DyLight 488 Labeled NB200-316G
DyLight 680 Labeled NB200-316FR
DyLight 755 Labeled NB200-316IR
PE Labeled NB200-316PE
PerCP Labeled NB200-316PCP

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Contact Information

Product PDFs


Gene Symbol CELF1

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