CRABP2 Antibody

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Western Blot: CRABP2 Antibody [NBP1-00765] - Western blot (WB) analysis of CRABP2 (P81) antibody in extracts from RAW264.7 cell

Product Details

Summary
Product Discontinued
View other related CRABP2 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-00765
    • Availability
      Product Discontinued

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CRABP2 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 50-100 of Human NCRABP-II.
Clonality
Polyclonal
Host
Rabbit
Gene
CRABP2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
Application Notes
Western blot (WB) analysis of CRABP2 (P81) pAb in extracts from RAW264.7 cell.
Theoretical MW
16 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

This antibody is reactive against Human, Mouse, Rat

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CRABP2 Antibody

  • cellular retinoic acid binding protein 2
  • Cellular retinoic acid-binding protein II
  • CRABP2
  • CRABP-II
  • CRABP-IIcellular retinoic acid-binding protein 2
  • RBP6

Background

The cellular retinoic acid-binding protein (CRABP)-I and a related isoform CRABP2 are nuclear receptors for retinoic acid (RA), an important regulator of cell growth and differentiation in fetal and adult tissues. These CRABP proteins mediate the downstream effects of RA in distinct ways. CRABP-I negatively regulates the activity of RA by enhancing the production of RAmetabolizing enzymes and increasing the rate at which RA is degraded. CRABP-II enhances the effects of RA by directly interacting with RA receptors (RAR) and, in turn, promoting the formation of RAR-RA complexes and stimulating RA-mediated gene transcription. Both CRABP-I and CRABP2 are expressed in the embryo, and CRABP-I is ubiquitously expressed in various adult tissues. The expression of CRABP-II is elevated in cells that synthesize relatively large amounts of RA, and it is also predominantly expressed in skin, uterus, ovary, and in the choroid plexus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CRABP2
Entrez