CPSF2 Antibody

Images

 
Western Blot: CPSF2 Antibody [NB100-79824] - CPSF100 on HeLa whole cell lysate using NB100-79824. CPSF100 was also immunoprecipitated by rabbit anti-CPSF100 antibodies NB100-79823 and NB100-79825.

Product Details

Summary
Product Discontinued
View other related CPSF2 Primary Antibodies

Order Details


    • Catalog Number
      NB100-79824
    • Availability
      Product Discontinued

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CPSF2 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 550 and 600 of human cleavage and polyadenylation specific factor 2, 100kDa using the numbering given in entry NP_059133.1 (GeneID 53981).
Clonality
Polyclonal
Host
Rabbit
Gene
CPSF2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunoprecipitation 1:10-1:500
Positive Control
CPSF2 Lysate (NBL1-09446)

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CPSF2 Antibody

  • cleavage and polyadenylation specific factor 2, 100kDa
  • Cleavage and polyadenylation specificity factor 100 kDa subunit
  • cleavage and polyadenylation specificity factor subunit 2
  • CPSF 100 kDa subunit
  • CPSF 100kDa subunit
  • CPSF100
  • KIAA1367cleavage and polyadenylation specific factor 2, 100kD subunit

Background

CPSF100/CPSF2 (cleavage and polyadenylation specific factor 2, 100 kDa subunit) is a subunit of the cleavage and polyadenylation specificity factor (CPSF) involved in mammalian mRNA 3'-end processing. CPSF, along with CstF (cleavage and stimulation factor), is critical for the recognition of cis-acting sequence elements on the pre-mRNA that dictate the site of cleavage and subsequent polyadenylation. CPSF exists as a complex of four proteins that includes CPSF160/CPSF1, CPSF100/CPSF2, CPSF73/CPSF3, and CPSF30/CPSF4. CPSF100/CPSF2 and CPSF73/CPSF3 are both members of the metallo-beta-lactamase superfamily of zinc-dependent hydrolases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CPSF2
Entrez
Uniprot