CPN1 Antibody Summary
Synthetic peptide, corresponding to amino acids 420-470 of Human CPN cat.
CPN1 cat (Q452) detects endogenous levels of CPN cat protein.
Immunogen affinity purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
- Western Blot 1:500-1:1000
Western blot (WB) analysis of CPN1 cat (Q452) pAb in extracts from RAW264.7 cell.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
This antibody is reactive against Human
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.2)
0.05% Sodium Azide
Immunogen affinity purified
Alternate Names for CPN1 Antibody
- Anaphylatoxin inactivator
- Arginine carboxypeptidase
- carboxypeptidase N polypeptide 1 50 kD
- Carboxypeptidase N polypeptide 1
- Carboxypeptidase N small subunit
- carboxypeptidase N, polypeptide 1
- carboxypeptidase N, polypeptide 1, 50kD
- CPNcarboxypeptidase N catalytic chain
- EC 3.4.17
- EC 22.214.171.124
- kininase I
- Lysine carboxypeptidase
- Plasma carboxypeptidase B
- SCPNcarboxypeptidase N catalytic subunit
- Serum carboxypeptidase N
Carboxypeptidase N (arginine carboxypeptidase or CPN) cleaves basic amino acid residues from the carboxy terminal of peptides and proteins. The enzyme plays a central role in regulating the biologic activity of peptides such as kinins and anaphylatoxins, and therefore is also known as kininase-1 and anaphylatoxin inactivator. CPN is a tetrameric complex consisting of two identical regulatory subunits (CPN reg) and two identical catalytic subunits (CPN cat). The two glycosylated CPN reg subunits protect the two CPN cat subunits and keep them in the circulation. CPN reg is a member of the leucinerich repeat family of proteins and the gene which encodes CPN reg maps to human chromosome 8p22-p23. CPN cat is a member of the regulatory B-type carboxypeptidase group and the gene which encodes CPN cat maps to human chromosome 10.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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