CPN1 Antibody

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Western Blot: CPN1 Antibody [NBP1-00764] - Western blot (WB) analysis of CPN1 cat (Q452) antibody in extracts from RAW264.7 cell

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-00764
    • Availability
      Product Discontinued

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CPN1 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 420-470 of Human CPN cat.
Specificity
CPN1 cat (Q452) detects endogenous levels of CPN cat protein.
Clonality
Polyclonal
Host
Rabbit
Gene
CPN1
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
Application Notes
Western blot (WB) analysis of CPN1 cat (Q452) pAb in extracts from RAW264.7 cell.
Theoretical MW
52 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

This antibody is reactive against Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CPN1 Antibody

  • ACBP
  • Anaphylatoxin inactivator
  • Arginine carboxypeptidase
  • carboxypeptidase N polypeptide 1 50 kD
  • Carboxypeptidase N polypeptide 1
  • Carboxypeptidase N small subunit
  • carboxypeptidase N, polypeptide 1
  • carboxypeptidase N, polypeptide 1, 50kD
  • CPNcarboxypeptidase N catalytic chain
  • EC 3.4.17
  • EC 3.4.17.3
  • FLJ40792
  • kininase I
  • kininase-1
  • Lysine carboxypeptidase
  • Plasma carboxypeptidase B
  • SCPNcarboxypeptidase N catalytic subunit
  • Serum carboxypeptidase N

Background

Carboxypeptidase N (arginine carboxypeptidase or CPN) cleaves basic amino acid residues from the carboxy terminal of peptides and proteins. The enzyme plays a central role in regulating the biologic activity of peptides such as kinins and anaphylatoxins, and therefore is also known as kininase-1 and anaphylatoxin inactivator. CPN is a tetrameric complex consisting of two identical regulatory subunits (CPN reg) and two identical catalytic subunits (CPN cat). The two glycosylated CPN reg subunits protect the two CPN cat subunits and keep them in the circulation. CPN reg is a member of the leucinerich repeat family of proteins and the gene which encodes CPN reg maps to human chromosome 8p22-p23. CPN cat is a member of the regulatory B-type carboxypeptidase group and the gene which encodes CPN cat maps to human chromosome 10.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CPN1
Entrez