Coronin-1a Antibody

Images

 
Western Blot: Coronin-1a Antibody [NB110-40715] - Detection of Human Coronin 1 on HeLa whole cell lysate using NB110-40715. Coronin 1 was also immunoprecipitated by rabbit anti-Coronin 1 antibodies NB110-40716 and ...read more
Immunohistochemistry-Paraffin: Coronin-1a Antibody [NB110-40715] - Human stomach carcinoma. Antibody used at a dilution of 1:1,000 (0.2ug/ml).

Product Details

Summary
Product Discontinued
View other related Coronin-1a Primary Antibodies

Order Details


    • Catalog Number
      NB110-40715
    • Availability
      Product Discontinued

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Coronin-1a Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 175 and 225 of human Coronin 1 (Coronin, Actin Binding Protein 1A) using the numbering given in entry NP_009005.1 (GeneID 11151).
Clonality
Polyclonal
Host
Rabbit
Gene
CORO1A
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 2-5 ug/mg lysate
Positive Control
Coronin-1a Lysate (NBL1-09395)
Publications
Read Publication using NB110-40715.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Coronin-1a Antibody

  • CLIPINA
  • clipin-A
  • CORO1
  • coronin, actin binding protein, 1A
  • coronin, actin-binding protein, 1A
  • coronin-1
  • coronin-1A
  • Coronin-like protein A
  • Coronin-like protein p57
  • FLJ41407
  • HCORO1
  • MGC117380
  • p57
  • TACOCLABP
  • Tryptophan aspartate-containing coat protein

Background

Coronin 1 was first isolated from Dictyostelium, but similar proteins have been identified in many species and individual cell types. The coronin-like protein in yeast promotes actin polymerization and also interacts with microtubules. Dictyostelium mutants lacking coronin are impaired in cytokinesis and all actin-mediated processes. Analysis of coronin-GFP fusions and knockout mutants shows that coronin participates in the remodelling of the cortical actin cytoskeleton that is responsible for phagocytosis and macropinocytosis. Likewise, in mammalian neutrophils, a coronin-like protein is also associated with the phagocytic apparatus. Coronin 1 binds actin and is found in noninfected macrophages, localised to the cortical microtubule network; in mycobacteria-infected macrophages, progressively relocalized and retained around the mycobacterial phagosomes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Coronin-1a Antibody (NB110-40715)(1)

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Positive Control Lysate(s)

Secondary Antibodies

 

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Bioinformatics

Gene Symbol CORO1A
Entrez
Uniprot