Complement Component C9 Antibody

Images

 
Western Blot: Complement Component C9 Antibody [NBP1-51349] - Analysis of C9 (H216) pAb at 1:500 dilution Lane1:Hela cell lysate Lane2:Raw264.7 cell lysate Lane3:PC12 cell lysate
Western Blot: Complement Component C9 Antibody [NBP1-51349] - Analysis of C9 (H216) pAb in extracts from COLO cells.

Product Details

Summary
Product Discontinued
View other related Complement Component C9 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-51349
    • Availability
      Product Discontinued

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Complement Component C9 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 171-220 of Human C9.
Specificity
C9 (H216) pAb detects endogenous levels of C9 protein.
Clonality
Polyclonal
Host
Rabbit
Gene
C9
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
Application Notes
Western blot (WB) analysis of C9 (H216) pAb in extracts from COLO cells.
Theoretical MW
63 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Complement Component C9 Antibody

  • complement component 9
  • Complement Component C9

Background

C9 is synthesised in the liver and monocytes, and is a plasma protein consisting of a single polypeptide chain of molecular weight 71kDa. Normal plasma concentration is 60mg/L. C9 forms part of the membrane attack complex (MAC) the cytolytic terminal complex of the complement pathways. C9 binds to the membrane associated C5b-8, binding of C9 to C5b-8 leads to the circular polymerisation of 12-18 C9 molecules. This is the basis of the hydrophilic, protein-walled, trans-membrane channel formed by the MAC, which leads to cell lysis and destruction.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol C9
Entrez