Complement Component C3a R Antibody (534625) [Alexa Fluor® 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
534625
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 488
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

Complement Component C3a R Antibody (534625) [Alexa Fluor® 488] Summary

Immunogen
NS0 mouse myeloma cell line transfected with human C3a R
Met1-Val482
Accession # Q16581
Specificity
Detects human Complement Component C3a R in direct ELISAs.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
C3AR1
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25-1 ug/10^6 cells
Application Notes
Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Buffer
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Preservative
0.09% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Complement Component C3a R Antibody (534625) [Alexa Fluor® 488]

  • AZ3B
  • AZ3BC3a anaphylatoxin chemotactic receptor
  • C3AR
  • C3a-R
  • C3AR1
  • C3ARcomplement component 3 receptor 1
  • C3R1
  • complement component 3a receptor 1
  • Complement Component C3a R
  • Complement Component C3aR
  • HNFAG09

Background

Complement Component 3a receptor (C3a R) is an ~90 kDa G-protein coupled 7-transmembrane sulfated glycoprotein expressed on myeloid peripheral blood leukocytes, and on activated lymphocytes, endothelial and internal organ epithelial cells. Engagement of C3a R by C3a activates mast cells and neutrophils, triggering degranulation in airways during asthmatic allergen challenges. It assists in Th2-type inflammatory reactions and stimulates leukocyte chemotaxis. Human C3a R extracellular regions share 50% and 42% amino acid identity with mouse and rat C3a R, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol C3AR1
Uniprot