Recombinant Mouse Common beta Chain Protein Summary
An un-tagged recombinant protein corresponding to the amino acids 18-141 of Mouse Common beta Chain
Amino Acid Sequence: MAPTRSPITV TRPWKHVEAI KEALNLLDDM PVTLNEEVEV VSNEFSFKKL TCVQTRLKIF EQGLRGNFTK LKGALNMTAS YYQTYCPPTP ETDCETQVTT YADFIDSLKT FLTDIPFECK KPVQK
|Details of Functionality
Measured in a cell proliferation assay using MC/9 cells.
The ED50 for this effect is less or equal to 0.5 ng/ml.
| Protein/Peptide Type
Biologically Active Protein
>95% pure by SDS-PAGE
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Phosphate buffered saline (pH 7.4), 10% glycerol
>95% pure by SDS-PAGE
Alternate Names for Recombinant Mouse Common beta Chain Protein
- beta, low-affinity
- CD131 antigen
- colony stimulating factor 2 receptor, beta, low-affinity(granulocyte-macrophage)
- Common beta Chain
- cytokine receptor common subunit beta
- GM-CSF R beta
- GM-CSF/IL-3/IL-5 receptor common beta subunit
- GM-CSF/IL-3/IL-5 receptor common beta-chain
- IL-3 R beta
- IL-5 R beta
- interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3receptor, beta (high affinity)
GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. Mouse GM-CSF protein is 125 amino acids and shares approximately 60% homology with the human GM-CSF protein. Recombinant mouse GM-CSF was expressed in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 2 years from date of receipt.
Customers Who Viewed This Item Also Viewed...
Applications: WB, Flow, CyTOF-ready
Applications: Flow, ICC/IF, IHC-Fr
Applications: Flow, CyTOF-ready, ICC, Neut
Species: Mu, Rt
Species: Hu, Ca
Applications: Flow, IHC, IHC-Fr, IHC-P, IP
Applications: WB, Flow, IHC, IHC-P
Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
Applications: WB, Neut
Applications: WB, Flow, IHC, CyTOF-ready
Species: Hu, Mu
Applications: WB, Simple Western, Flow, IHC, CyTOF-ready
Applications: Func, PAGE
Publications for Common beta Chain Protein (NBC1-18483) (0)
There are no publications for Common beta Chain Protein (NBC1-18483).
By submitting your publication information earn gift cards and discounts for future purchases.
Reviews for Common beta Chain Protein (NBC1-18483) (0)
There are no reviews for Common beta Chain Protein (NBC1-18483).
By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
- Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
- Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
- 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen
FAQs for Common beta Chain Protein (NBC1-18483) (0)
Additional Common beta Chain Products
Bioinformatics Tool for Common beta Chain Protein (NBC1-18483)
Discover related pathways, diseases and genes to Common beta Chain Protein (NBC1-18483). Need help?
Read the Bioinformatics Tool Guide
for instructions on using this tool.
PTMs for Common beta Chain Protein (NBC1-18483)
Learn more about PTMs related to Common beta Chain Protein (NBC1-18483).
Blogs on Common beta Chain