Common beta Chain Recombinant Protein Summary
A recombinant protein corresponding to amino acids 18 - 141 of CSF2RB.
Amino Acid Sequence: MAPTRSPITVTRPWKHVEAIKEALNLLDDMPVTLNEEVEVVSNEFSFKKLTCVQTRLKIFEQGLRGNFTKLKGALNMTASYYQTYCPPTPETDCETQVTTYADFIDSLKTFLTDIPFECKKPVQK
Packaging, Storage & Formulations
Store at -80C. Avoid freeze-thaw cycles.
Liquid in phosphate-buffered saline (PBS), pH 7.4, 10% glycerol
The purity of this protein is > 95% by SDS-PAGE. Molecular weight is 14 kDa (125 aa), confirmed by MALDI-TOF.
Alternate Names for Common beta Chain Recombinant Protein
- beta, low-affinity
- CD131 antigen
- colony stimulating factor 2 receptor, beta, low-affinity(granulocyte-macrophage)
- cytokine receptor common subunit beta
- GM-CSF R beta
- GM-CSF/IL-3/IL-5 receptor common beta subunit
- GM-CSF/IL-3/IL-5 receptor common beta-chain
- IL-3 R beta
- IL-5 R beta
- interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3receptor, beta (high affinity)
GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. Mouse GM-CSF protein is 125 amino acids and shares approximately 60% homology with the human GM-CSF protein. Recombinant mouse GM-CSF was expressed in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
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