Common beta Chain Antibody (1C1) [FITC]

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Flow Cytometry: Common beta Chain Antibody (1C1) [FITC] [NBP1-54512] - Analysis of CDw131/common beta subunit expression on common beta subunit transfected CHO cells. Open histogram indicates the reaction of isotypic ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-54512
    • Availability
      Product Discontinued

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Common beta Chain Antibody (1C1) [FITC] Summary

Immunogen
The immunogen for this antibody was CD131.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CSF2RB
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000

Reactivity Notes

This antibody is reactive to Human.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS and 1.0% BSA
Preservative
0.05% Sodium Azide
Concentration
.05 mg/ml
Purity
Protein A or G purified

Alternate Names for Common beta Chain Antibody (1C1) [FITC]

  • beta, low-affinity
  • CD131 antigen
  • CD131
  • CDw131
  • colony stimulating factor 2 receptor, beta, low-affinity(granulocyte-macrophage)
  • Common beta Chain
  • CSF2RB
  • cytokine receptor common subunit beta
  • GM-CSF R beta
  • GM-CSF/IL-3/IL-5 receptor common beta subunit
  • GM-CSF/IL-3/IL-5 receptor common beta-chain
  • IL-3 R beta
  • IL3RB
  • IL-5 R beta
  • interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3receptor, beta (high affinity)

Background

The 1C1 monoclonal antibody reacts with the human CD131 molecule, also known as the common beta subunit (betaC). The common beta subunit associates with the specific alpha subunits of IL-3 receptor, IL-5 receptor and GM-CSF receptor to form high affinity receptors for these cytokines. These cytokine receptors are expressed by neutrophils, eosinophils, monocytes, endothelial cells, fibroblasts and hematopoietic progenitor cells and play a crucial role in growth/activation of eosinophils and in the inflammatory response.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CSF2RB
Entrez