Common beta Chain Antibody (1C1) Summary
The immunogen for this antibody was CD131.
Protein A or G purified
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- Western Blot 1:100-1:2000
- Flow Cytometry 1:10-1:1000
- Immunoprecipitation 1:10-1:500
The 1C1 antibody has been tested by flow cytometric analysis of human peripheral blood leukocytes. This can be used at less than or equal to 1 ug per test. Cell number should be determined empirically but can range from 10^5to 10^8cells/test.
This antibody is reactive to Human.
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
Aqueous, may contain carrier protein/stabilizer.
0.09% Sodium Azide
Protein A or G purified
Alternate Names for Common beta Chain Antibody (1C1)
- beta, low-affinity
- CD131 antigen
- colony stimulating factor 2 receptor, beta, low-affinity(granulocyte-macrophage)
- Common beta Chain
- cytokine receptor common subunit beta
- GM-CSF R beta
- GM-CSF/IL-3/IL-5 receptor common beta subunit
- GM-CSF/IL-3/IL-5 receptor common beta-chain
- IL-3 R beta
- IL-5 R beta
- interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3receptor, beta (high affinity)
The 1C1 monoclonal antibody reacts with the human CD131 molecule, also known as the common beta subunit (betaC). The common beta subunit associates with the specific alpha subunits of IL-3 receptor, IL-5 receptor and GM-CSF receptor to form high affinity receptors for these cytokines. These cytokine receptors are expressed by neutrophils, eosinophils, monocytes, endothelial cells, fibroblasts and hematopoietic progenitor cells and play a crucial role in growth/activation of eosinophils and in the inflammatory response.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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