Coagulation Factor VII Antibody (RFF-VII/2)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, RIA
Clone
RFF-VII/2
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Coagulation Factor VII Antibody (RFF-VII/2) Summary

Immunogen
Purified Factor VII
Specificity
VII
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
F7
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Radioimmunoassay 1:100-1:2000
Application Notes
Binds to a conformational epitope and will not bind to reduced Factor VII.
Publications
Read Publication using NBP1-45148.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein A or G purified

Alternate Names for Coagulation Factor VII Antibody (RFF-VII/2)

  • coagulation factor VII (serum prothrombin conversion accelerator)
  • Coagulation Factor VII
  • EC 3.4.21
  • EC 3.4.21.21
  • Eptacog alfa
  • F7
  • FVII coagulation protein
  • proconvertin
  • Serum prothrombin conversion accelerator
  • SPCA

Background

Factor VII is a 50kDa multi-domain, single chain plasma glycoprotein synthesized in the liver and having abnormal circulating concentration of between 400 and 600 ug/L. It is essential for blood coagulation. Factor VII is converted to the active, two chain, serine protease Factor VIIa through cleavage by thrombin, factor Xa, factor IXa or factor XIIa. Factor VIIa converts factor X to factor Xa, which in turn converts prothrombin to thrombin.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Coagulation Factor VII Antibody (NBP1-45148)(1)

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for Coagulation Factor VII Antibody (NBP1-45148). (Showing 1 - 1 of 1 FAQ).

  1. Can you provide more detailed information about the exact epitope sequence of this antibody?
    • The immunogen was the full-length human factor VII protein (rather than a shorter immunogenic peptide). The epitope of NBP1-45148 has not been mapped, and so we do not have any information about where on factor VII these antibodies bind.

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol F7
Entrez
Uniprot