Recombinant Mouse CNOT7 Protein

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SDS-Page: Recombinant Mouse CNOT7 Protein [NBP1-72420] - 15% SDS-PAGE (3ug)

Product Details

Summary
Reactivity MuSpecies Glossary
Applications PAGE
Concentration
1 mg/ml

Order Details

Recombinant Mouse CNOT7 Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-248 of Mouse CNOT7

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMPAATVD HSQRICEVWA CNLDEEMKKI RQVIRKYNYV AMDTEFPGVV ARPIGEFRSN ADYQYQLLRC NVDLLKIIQL GLTFMNEQGE YPPGTSTWQF NFKFNLTEDM YAQDSIELLT TSGIQFKKHE EEGIETQYFA ELLMTSGVVL CEGVKWLSFH SGYDFGYLIK ILTNSNLPEE ELDFFEILRL FFPVIYDVKY LMKSCKNLKM FFEDHIDDAK YCGHLYGLGS GSSYVQNGTG NAYEEEASKQ S

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
CNOT7
Purity
>80%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
31.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT
Preservative
No Preservative
Concentration
1 mg/ml
Purity
>80%, by SDS-PAGE

Alternate Names for Recombinant Mouse CNOT7 Protein

  • BTG1 binding factor 1
  • BTG1-binding factor 1
  • CAF-1
  • CAF1carbon catabolite repressor protein (CCR4)-associative factor 1
  • CCR4-associated factor 1
  • CCR4-NOT transcription complex subunit 7
  • CCR4-NOT transcription complex, subunit 7
  • hCAF-1

Background

CNOT7, also known as CCR4-Not transcription complex, subunit 7, is a ubiquitous transcription factor. It is a component of the CCR4 complex which functions as a general transcription regulation complex. CNOT7 also binds to an anti-proliferative protein, B-cell translocation protein 1 (BTG1), which negatively regulates cell proliferation. Recombinant mouse CNOT7 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol CNOT7