Clusterin/APOJ Antibody

Images

 
Western Blot: Clusterin/APOJ Antibody [NBP1-77258] - Human brain tissue lysate with APOJ / Clusterin body at (A) 0.5 and (B) 1 ug/ml.
Immunocytochemistry/ Immunofluorescence: Clusterin/APOJ Antibody [NBP1-77258] - Staining of Clusterin in mouse brain tissue with Clusterin Antibodyat 20 ug/mL.
Immunohistochemistry: Clusterin/APOJ Antibody [NBP1-77258] - Staining of Clusterin in mouse brain tissue with Clusterin Antibodyat 5 ug/mL.
Immunocytochemistry/ Immunofluorescence: Clusterin/APOJ Antibody [NBP1-77258] - Staining of Clusterin in human brain tissue with Clusterin antibody at 20 ug/ml.
Immunohistochemistry: Clusterin/APOJ Antibody [NBP1-77258] - Staining of human brain tissue with antibody at 5 ug/mL.

Product Details

Summary
Product Discontinued
View other related Clusterin/APOJ Primary Antibodies

Order Details


    • Catalog Number
      NBP1-77258
    • Availability
      Product Discontinued

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Clusterin/APOJ Antibody Summary

Immunogen
Antibody was raised recombinant human Clusterin isoform 1.
Clonality
Polyclonal
Host
Rabbit
Gene
CLU
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunofluorescence
Application Notes
Clusterin antibody can be used for the detection of Clusterin by Western blot at 0.5 - 1 mg/ml.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Clusterin/APOJ Antibody

  • 40
  • 40, sulfated glycoprotein 2
  • Aging-associated gene 4 protein
  • aging-associated protein 4
  • APOJ
  • apo-J
  • Apolipoprotein J
  • CLI
  • CLIclusterin (complement lysis inhibitor, SP-40
  • CLU
  • Clusterin
  • Complement cytolysis inhibitor
  • complement lysis inhibitor
  • Complement-associated protein SP-40
  • Ku70-binding protein 1
  • KUB1SGP2
  • MGC24903
  • NA1/NA2
  • SGP-2
  • SP-40
  • sulfated glycoprotein 2
  • Testosterone-repressed prostate message 2
  • testosterone-repressed prostate message 2, apolipoprotein J)
  • TRPM-2
  • TRPM-2TRPM2

Background

Clusterin, also known as Apolipoprotein J (ApoJ), is a ubiquitous multifunctional glycoprotein that can interact with a broad spectrum of molecules such as complement components, various receptors, and the Alzheimer's b-amyloid peptide. Clusterin expression is increased in Alzheimer's disease brain tissue and clusterin-immunoreactive amyloid plaques are found associated with phospho-tau-positive dystrophic neurites and it has been suggested that clusterin facilitates the conversion of diffuse b-amyloid deposits into amyloid and enhances tau phosphorylation in neurites around these plaques. Other reports show that clusterin expression is decreased in proliferating cells and is upregulated in quiescent and senescent cells, suggesting that it may also play a role in aging and tumorigenesis suppression. Clusterin exists in at least two distinct isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for APOJ / Clusterin Antibody (NBP1-77258)

Discover related pathways, diseases and genes to APOJ / Clusterin Antibody (NBP1-77258). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for APOJ / Clusterin Antibody (NBP1-77258)

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Pathways for APOJ / Clusterin Antibody (NBP1-77258)

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PTMs for APOJ / Clusterin Antibody (NBP1-77258)

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Research Areas for APOJ / Clusterin Antibody (NBP1-77258)

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Contact Information

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Bioinformatics

Gene Symbol CLU
Entrez
Uniprot