Claudin-7 Antibody

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Immunohistochemistry-Paraffin: Claudin 7 Antibody [NBP1-35677] Human Colon Carcinoma.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-35677
    • Availability
      Product Discontinued

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Claudin-7 Antibody Summary

Immunogen
A synthetic peptide from C-terminus of human claudin 7 protein
Specificity
This product is specific for Claudin 7
Clonality
Polyclonal
Host
Rabbit
Gene
CLDN7
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:200
Application Notes
IHC-P: Ready to use for 10 min at RT.Staining of formalin-fixed tissues requires boiling tissue sections in 10mMcitrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user.

Reactivity Notes

This product is specific for Human, Mouse, Rat.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
10mM PBS (pH 7.4) and 1.0% BSA
Preservative
0.1% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Claudin-7 Antibody

  • CEPTRL2
  • claudin 7
  • claudin-1
  • Claudin7
  • Claudin-7
  • CLDN7
  • CLDN-7
  • clostridium perfringens enterotoxin receptor-like 2
  • CPETRL2

Background

The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the Claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Claudin expression is highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. mRNA studies indicate that claudin-7 is specifically expressed in mouse lung and kidney, but not in heart, brain, spleen, liver, skeletal muscle or testis. The gene encoding human claudin-7 maps to chromosome 17p13.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CLDN7
Entrez